• 介绍：

  Paeonol 是一种从牡丹中提取的活性物质，可抑制 MAO-A 和 MAO-B，IC50 分别为 54.6 μM 和 42.5 μM。

• 熔点： 48-50°C(lit.)

• 沸点： 154 °C / 20mmHg

• 外观： 白色或微黄色有光泽的针状结晶，无色针状结晶（乙醇）。

• 溶解性： Ethanol  :  50  mg/mL  (300.90  mM;  Need  ultrasonic)
  
  DMSO  :  ≥  38  mg/mL  (228.68  mM)
  
  H2O  :  1  mg/mL  (6.02  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 46. [IF=7.9] Meng Zhao et al."Paeonol alleviates ulcerative colitis in mice by increasing short-chain fatty acids derived from Clostridium butyricum."PHYTOMEDICINE.10.1016/j.phymed.2023.155056

• 45. [IF=1.8] Yue Qian et al."Si Miao San relieves hyperuricemia by regulating intestinal flora."BIOMEDICAL CHROMATOGRAPHY.2023 Dec;:e5807

• 44. [IF=5.4] Mingxiang Xie et al."Molecular mechanism of PSORI-CM01 for psoriasis by regulating the inflammatory cytokines network."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;318:116935

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• 42. [2.464] Hao Mingxuan et al."Paeonol Inhibits Glioma Growth In Vivo and In Vitro by Inducing Apoptosis and Cell Cycle Arrest."Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy.2023 Mar;:1-9

• 41. [3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683

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• 39. [IF=3.385] Yaxue Li et al."The effect of dietary paeonol on growth performance, antioxidant enzyme activities and gene expressions of Genetic Improvement of Farmed Tilapia juveniles (Oreochromis niloticus)."Aquaculture Reports.2022 Oct;26:101302

• 38. [IF=4.996] Yuan Jie et al."Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology."Scientific Reports.2022 Jul;12(1):1-24

• 37. [IF=5.135] Lijuan Yu et al."Acetylferulic paeonol ester: A new feed additive reduces lipid accumulation in the liver of Nile tilapia (Oreochromis niloticus) by modulating lipid and glucose metabolism."AQUACULTURE.2022 Dec;561:738671

• 36. [IF=2.952] Shouzhu Xu et al."Paeonol alleviates lipopolysaccharide‑induced hepatocytes injury through alteration of mitochondrial function and NF‑κB translocation."Mol Med Rep. 2021 Nov;24(5):1-9

• 35. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 34. [IF=3.512] Yahong Chen et al."Identification of Potential Human Ryanodine Receptor 1 Agonists and Molecular Mechanisms of Natural Small-Molecule Phenols as Anxiolytics."Acs Omega. 2021;XXXX(XXX):XXX-XXX

• 33. [IF=3.69] Qianni Duan et al."Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2."J Ethnopharmacol. 2020 Mar;249:112405

• 32. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002

• 31. [IF=3.996] Liu Dong-Hai et al."Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats."Neurochem Res. 2019 Nov;44(11):2556-2565

• 30. [IF=3.998] Mei Liyan et al."Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p."Sci Rep-Uk. 2019 Dec;9(1):1-15

• 29. [IF=4.36] Xiaoli Zhao et al."Transcriptomic study of the mechanism by which the Kai Yu Zhong Yu recipe improves oocyte quality in a stressed mouse model."J Ethnopharmacol. 2021 Oct;278:114298

• 28. [IF=4.53] Du Jikun et al."Paeonol triggers apoptosis in HeLa cervical cancer cells: the role of mitochondria-related caspase pathway."Psychopharmacology. 2021 Mar 12

• 27. [IF=5.875] Fangyuan Wang et al."Paeonol-loaded PLGA nanoparticles as an oral drug delivery system: Design, optimization and evaluation."Int J Pharmaceut. 2021 Jun;602:120617

• 26. [IF=6.165] Jinpeng Liu et al."Temperature-sensitive lyotropic liquid crystals as systems for transdermal drug delivery."J Mol Liq. 2021 Mar;326:115310

• 25. [IF=7.514] Lijuan Yu et al."Synthesis and evaluation of acetylferulic paeonol ester and ferulic paeonol ester as potential antioxidants to inhibit fish oil oxidation."Food Chem. 2021 Dec;365:130384

• 24. [IF=3.361] Xia Liu et al."Paeonol attenuates acute lung injury by inhibiting HMGB1 in lipopolysaccharide-induced shock rats."Int Immunopharmacol. 2018 Aug;61:169

• 23. [IF=5.076] Huichao Xie et al."An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel."Nanomaterials-Basel. 2019 Feb;9(2):147

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输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *