• 介绍：

   Omeprazole (H 16868) 是一种质子泵 (proton pump) 抑制剂 (PPI)，有潜力用于胃肠道疾病的研究。Omeprazole 竞争性抑制 CYP2C19 活性，Ki 为 2 到 6 μM。Omeprazole 还抑制革兰氏阳性菌和革兰氏阴性菌生长。Omeprazole 是中性鞘磷脂酶 (N-SMase) 的抑制剂(外泌体抑制剂)。

• 熔点： 156°C

• 沸点： 600°C at 760 mmHg

• 外观： white solid

• 溶解性： DMSO  :  ≥  100  mg/mL  (289.50  mM)
  
  H2O  :  0.67  mg/mL  (1.94  mM;  Need  ultrasonic)

• 敏感性： 易吸潮；对光敏感

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 14. [IF=2.9] Yuan Wang et al."Chemometrics-based Chemical Analysis of Myrrh and Its Vinegar-processed Products by UPLC-MS/MS."CHEMISTRY & BIODIVERSITY.2024 Jan;:e202301782

• 13. [IF=8.2] Na Li et al."A rapid-floating natural polysaccharide gel–raft with double-effect for the treatment of gastroesophageal reflux disease."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Mar;261:129667

• 12. [IF=3.9] Kunhui Sun et al."A Multichannel Fluorescent Array Sensor for Discrimination of Different Types of Drug-Induced Kidney Injury."SENSORS.2023 Jan;23(13):6114

• 11. [IF=6.911] Zhenwei Xiao et al."An effective pretreatment technique based on multi-walled carbon nanotubes to reduce the matrix effect in plasma samples analyzed by a new type probe electrospray ionization method."ANALYTICA CHIMICA ACTA.2023 Jul;1263:341268

• 10. [5.364] Lisu Li et al."Bletilla striata Polysaccharide Nanoparticles Improved the Therapeutic Efficacy of Omeprazole on the Rat Gastric Ulcer Induced by Ethanol."MOLECULAR PHARMACEUTICS.2023;XXXX(XXX):XXX-XXX

• 9. [IF=5.719] Baoming Tian et al."Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats."Nutrients. 2022 Jan;14(7):1476

• 8. [IF=3.503] Yuzhu Zhang et al."Effects of psoralen on the pharmacokinetics of anastrozole in rats."Pharm Biol. 2018;56(1):433-439

• 7. [IF=3.659] Rong Qian et al."In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori."Bmc Complem Altern M. 2016 Dec;16(1):1-8

• 6. Rong, Qian, et al. "In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (SY Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori." BMC complementary and alternative medicine 1

• 5. Zhang, Yuzhu, et al. "Effects of psoralen on the pharmacokinetics of anastrozole in rats." Pharmaceutical biology 56.1 (2018): 433-439.https://doi.org/10.1080/13880209.2018.1501584

• 4. 魏文增,赵宁宁,林颖烽,王瑾,王宫.Cocktail探针法评价牛樟芝醇提物对人CYP450酶活性的影响[J].科技风,2021(03):139-140.

• 3. 陈瑞,周维,张丽,朱高峰,黄静,汤磊.树豆酮酸A对人肝微粒体中5种常见细胞色素P_(450)酶的体外抑制作用研究[J].中国药房,2021,32(02):195-200.

• 2. 魏文增,赵宁宁,林颖烽,王瑾,王宫.Cocktail探针法评价牛樟芝醇提物对人CYP450酶活性的影响[J].科技风,2021(03):139-140.

• 1. 景娴 江海 陈琛.UPLC-MS法同时检测大鼠血浆中6种CYP450探针药物浓度[J].陕西理工大学学报(自然科学版) 2018 34(01):59-65.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *