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• 介绍：转铁蛋白是血浆中主要的铁传递蛋白，为细胞分化和细胞代谢提供所需的铁。研究发现 所有的细胞生长都离不开转铁蛋白。不但维持正常的细胞代谢依赖于以生物活性形态存在的 铁，铁还是一些酶的辅助因子，比如 RNA 聚合酶，DNA 合成酶。同时也是血红蛋白的重要 组成部分。

• 转铁蛋白是血浆糖蛋白，从血浆中分离而来，牛转铁蛋白以两种分子形态存在，分子量 分别为 74KD 和 78KD。每个转铁蛋白分子通过 C 端和 N 端结构位点可以结合两分子铁离子， 所以转铁蛋白以三种形态存在：脱铁（不结合铁离子），饱和铁（结合两分子铁离子）和部 分饱和，在生理情况下，转铁蛋白分子仅有 1/3 被铁饱和。

• 使用说明： 转铁蛋白对于绝大部分细胞系在无血清培养基中生长是必需的，研究表明饱和铁形态的 转铁蛋白对于促进细胞生长是最有效的形态。对于杂交瘤，黏连细胞和悬浮细胞系，在细胞 培养过程中，应保持培养基中转铁蛋白浓度在 0.5-100μ g/ml。针对不同的细胞系，需要选 择最合适的浓度。

• 转铁蛋白冻干粉需要保存在冷藏状态下，使用之前再溶解。一般用 PBS 或者其它合适 的溶剂在室温下将转铁蛋白冻干粉溶解成储液，浓度在 0.5-2.0mg/ml,然后用无菌滤膜进行过 滤，滤液可在无菌条件下 2-8℃保存 30 天。

• 外观： 冻干粉末

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 32. [IF=5.5] Zhou Limei et al."Transferrin modified PEG–PLGA nanoparticles: highly effective notoginsenoside R1 formulations for the treatment of ulcerative colitis."Journal of Pharmaceutical Investigation.2024 Jan;:1-17

• 31. [IF=5.9] Cheng Yun-Mou et al."An immortal porcine preadipocyte cell strain for efficient production of cell-cultured fat."Communications Biology.2023 Nov;6(1):1-13

• 30. [IF=5.7] Guo Xu et al."Imidazole-octyl mixed-mode stationary phase based on macroporous silica for the purification of ovomucoid and ovotransferrin."MICROCHIMICA ACTA.10.1007/s00604-023-05986-7

• 29. [IF=26.6] Zhao Henan et al."Artificial Macrophage with Hierarchical Nanostructure for Biomimetic Reconstruction of Antitumor Immunity."Nano-Micro Letters.10.1007/s40820-023-01193-4

• 28. [IF=15.1] Ziyuan Wang et al."A bioinspired fluorescent probe based on metal–organic frameworks to selectively enrich and detect amyloid-β peptide."CHEMICAL ENGINEERING JOURNAL.2023 Aug;470:144124

• 27. [IF=6.59] Jiahui Liu et al."Self-assembly and label-free fluorescent aptasensor based on deoxyribonucleic acid intercalated dyes for detecting lactoferrin in milk powder.."Frontiers in Nutrition.2022 Sep;9:992188-992188

• 26. [IF=3.318] Jiawei Liu et al."Pseudo-mercaptoethyl pyridine functionalized polyhedral oligomeric silsesquioxane-graphene composite via thiol-ene click reaction for highly selective purification of antibody."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE B

• 25. [IF=17.694] Tian Jia-Hong et al."A facile way to construct sensor array library via supramolecular chemistry for discriminating complex systems."Nature Communications.2022 Jul;13(1):1-12

• 24. [IF=2.98] Chen Rui et al."Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway."MOLECULAR GENETICS AND GENOMICS.2022 Jun;:1-11

• 23. [IF=10.383] Xiaoming Yang et al."A Multifunctional Vanadium-Iron-Oxide Nanoparticle Eradicates Hepatocellular Carcinoma via Targeting Tumor and Endothelial Cells."ACS Applied Materials & Interfaces.2022;XXXX(XXX):XXX-XXX

• 22. [IF=6.057] Zhi-Heng Pan et al."Poly(caffeic acid)-coated molecularly imprinted magnetic nanoparticles for specific and ultrasensitive detection of glycoprotein."Talanta. 2022 May;241:123240

• 21. [IF=9.229] Miaomiao Han et al."Amyloid Protein-Biofunctionalized Polydopamine Nanoparticles Demonstrate Minimal Plasma Protein Fouling and Efficient Photothermal Therapy."Acs Appl Mater Inter. 2022;XXXX(XXX):XXX-XXX

• 20. [IF=2.649] Xingzhen Zhang et al."Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma."Med Sci Monitor. 2019; 25: 9737–9751

• 19. [IF=4.155] Chunling Zhu et al."Construction of synergistic therapy system with multiple therapeutic effects based on CuS@Tf nanodots."J Inorg Biochem. 2020 Aug;209:111100

• 18. [IF=5.875] Yanyan Yin et al."Cascade catalytic nanoplatform based on ions interference strategy for calcium overload therapy and ferroptosis."Int J Pharmaceut. 2021 Sep;606:120937

• 17. [IF=7.1] Rui Duan et al."Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein."Sensor Actuat B-Chem. 2021 Mar;330:129310

• 16. [IF=10.618] Cai-Feng Shi et al."Ultrasensitive plasmon enhanced Raman scattering detection of nucleolin using nanochannels of 3D hybrid plasmonic metamaterial."Biosens Bioelectron. 2021 Apr;178:113040

• 15. [IF=6.331] Wei Zhao et al."Transferrin-decorated, MoS2-capped hollow mesoporous silica nanospheres as a self-guided chemo–photothermal nanoplatform for controlled drug release and thermotherapy."J Mater Chem B. 2017 Sep;5(35):7403-7414

• 14. [IF=9.518] Guichun Mo et al."A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha-fetoprotein."Biosens Bioelectron. 2019 Feb;126:558

• 13. [IF=13.273] Aitang Zhang et al."An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually controlled drug release."Chem Eng J. 2018 Jun;342:120

• 12. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu, An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control

• 11. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu, An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control

• 10. Zhang, Aitang, et al. "A Target‐Directed Chemo‐Photothermal System Based on Transferrin and Copolymer‐Modified MoS2 Nanoplates with pH‐Activated Drug Release." Chemistry–A European Journal 23.47 (2017): 11346-11356.https://doi.org/10.1002/chem.201701916

• 9. Guichun Mo, Xinxin He, Chunqin Zhou, Dongmei Ya, Jinsu Feng, Chunhe Yu, Biyang Deng, A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha-

• 8. Zhu, Chunling, et al. "Construction of synergistic therapy system with multiple therapeutic effects based on CuS@ Tf nanodots." Journal of Inorganic Biochemistry 209 (2020): 111100.https://doi.org/10.1016/j.jinorgbio.2020.111100

• 7. 吕娟,周刚,李振莲,杜艳,朱叶青.凝胶过滤色谱法测定蛋白胨中多肽的相对分子质量分布[J].食品安全质量检测学报,2020,11(15):5131-5136.

• 6. 杨卓一,陈会,白思益,帕梅拉·帕尔哈提,侯敬丽,袁运生.伴刀豆球蛋白A诱导肝细胞损伤的磷酸化蛋白质组学研究[J].上海交通大学学报(医学版),2021,41(01):1-7.

• 5. 肖语涵,胡月,黄沛力.荧光光谱与等温滴定量热法研究碲化镉量子点与转铁蛋白的相互作用[J].毒理学杂志,2020,34(06):449-453.

• 4. 罗明志, 余培丽, 金阳,等. 血根碱对大鼠气道平滑肌细胞生物力学特性的影响[J]. 生物医学工程学杂志, 2018, v.35(04):89-97.

• 3. 江力, 谈弋, 王军. 转铁蛋白修饰的甲基莲心碱纳米脂质体的研制及脑靶向性考察[J]. 中国药师, 2019, 22(03):447-450.

• 2. 杨凯,李一鹏,刘英富,程远驰,汤锋武,梁冰,徐忠伟,陈旭义.大鼠皮质少突胶质细胞培养条件的优化[J].中国组织工程研究,2016,20(29):4328-4333.

• 1. 吕娟 周刚 李振莲 杜艳 朱叶青.凝胶过滤色谱法测定蛋白胨中多肽的相对分子质量分布[J].食品安全质量检测学报 2020 11(15):5131-5136.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *