• 介绍： 药理药效：具有减肥降脂的作用。

• 熔点： 165.5°C

• 沸点： 430.7°Cat760mmHg

• 比旋光度： (c, 1 in EtOH)-164

• 外观： 白色粉末

• 溶解性： 易溶于苯、乙醚、氯仿、卤代烷烃等极性较低的有机溶剂，在丙酮、乙醇等亲水性有机溶剂中也有较好的溶解度，而在水中溶解度较小或几乎不溶

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 38. [IF=8.4] Yanzhao Liu et al."Enzyme-Assisted Extraction of Nuciferine and Quercetin from Lotus Leaves Using the Aqueous-Based Method: A Sustainable Approach."ACS Sustainable Chemistry & Engineering.2023;11(50):17687–17696

• 37. [IF=6] Jiahuan Xu et al."A new strategy for the preparation of nuciferine from lotus leaf via expanded bed adsorption extraction integrated with pH dependent liquid-liquid extraction and cooling crystallization."Sustainable Chemistry and Pharmacy.2024 Feb;37:1014

• 36. [IF=3.5] Zhiyuan Fang et al."Nuciferine protects bovine hepatocytes against free fatty acid-induced oxidative damage by activating the transcription factor EB/peroxisome proliferator-activated receptor γ coactivator 1 alpha pathway."JOURNAL OF DAIRY SCIENCE.10.3168

• 35. [5.464] Jiahuan Xu et al."D-limonene as an alternative for the extraction and purification of nuciferine from lotus leaf via multi-stage vortex assisted two-phase solvent extraction integrated with solid phase extraction using mesoporous material SBA-15 as adsorb

• 34. [2.215] Qin Li et al."Valorization of lotus leaf by in-situ expanded bed adsorption and ultrasonic assisted desorption."CHEMICAL ENGINEERING & TECHNOLOGY.2022 Dec;:

• 33. [5.895] Jinxia Li et al."Nuciferine Ameliorates Nonesterified Fatty Acid-Induced Bovine Mammary Epithelial Cell Lipid Accumulation, Apoptosis, and Impaired Migration via Activating LKB1/AMPK Signaling Pathway."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2022;XXXX(

• 32. [7.291] Yu Yuetong et al."Functional characterization and key residues engineering of a regio-promiscuity O-methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in Nelumbo nucifera."Horticulture Research.2022 Dec;:

• 31. [IF=3.2] Chenyang Hao et al."Nontarget Metabolites of Rhizomes of Edible Sacred Lotus Provide New Insights into Rhizome Browning."JOURNAL OF FOOD QUALITY.2022 Oct 26;2022:3943052

• 30. [IF=0] Danni Wang et al."Identification of Q-Markers from Hedan Tablet by employing “spider-web” mode and taking compounds’ hepatotoxicity into account."Chinese Herbal Medicines.2022 Aug;:

• 29. [IF=4.212] Chang Chen et al."Nuciferine attenuates acute ischemic stroke in a rat model: a metabolomic approach for the mechanistic study."Molecular Omics.2022 Jul;:

• 28. [IF=5.307] Yu-kai Zhang et al."Synthesis and bioactivity evaluation of novel nuciferine derivatives with antihyperuricemia and nephroprotective effects."BIOORGANIC CHEMISTRY.2022 Sep;126:105916

• 27. [IF=7.491] Yeqing Ruan et al."Processing tactics for low-cost production of pure nuciferine from lotus leaf."ULTRASONICS SONOCHEMISTRY. 2022 May;86:106026

• 26. [IF=3.394] Chang Chen et al."Protective Effects of Nuciferine in Middle Cerebral Artery Occlusion Rats Based on Transcriptomics."Brain Sciences. 2022 May;12(5):572

• 25. [IF=11.413] Xiliang Du et al."Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy–lysosomal pathway."Acta Pharm Sin B. 2021 Dec;:

• 24. [IF=1.902] Yongjing Liu et al."Evaluation of Green and Efficient deep eutectic solvents as media for extracting Alkaloids from Lotus Leaf."Biomedical Chromatography. 2021 Dec 06

• 23. [IF=7.514] YueTong Yu et al."Identification and Quantification of Oligomeric Proanthocyanidins, Alkaloids, and Flavonoids in Lotus Seeds: A Potentially Rich Source of Bioactive Compounds."Food Chem. 2022 Jan;:132124

• 22. [IF=3.373] Na Zhang et al."TLC–MS identification of alkaloids in Leonuri Herba and Leonuri Fructus aided by a newly developed universal derivatisation reagent optimised by the response surface method."Phytochem Analysis. 2021 May;32(3):242-251

• 21. [IF=3.935] Peiliang Zhang et al."TLC-electrostatic field induced spray ionization-MS analysis of diverse structural skeletons and its coupling with TLC bioautography for characterization of lipase inhibitory components in American ginseng."J Pharmaceut Biomed. 2019

• 20. [IF=4.451] Haiyan Wen et al."Nuciferine attenuates the progression of osteoarthritis by targeting PI3K/Akt/NF-κB signaling pathway."J Funct Foods. 2021 Nov;86:104682

• 19. [IF=5.396] Zhen Shi et al."Nuciferine improves high-fat diet-induced obesity via reducing intestinal permeability by increasing autophagy and remodeling the gut microbiota."Food Funct. 2021 Jul;12(13):5850-5861

• 18. [IF=3] Zhang Pengyu et al."Discovery of novel antagonists on β2-adrenoceptor from natural products using a label-free cell phenotypic assay."N-S Arch Pharmacol. 2018 Dec;391(12):1411-1420

• 17. [IF=3.174] Chen Xingxing et al."Nuciferine alleviates LPS-induced mastitis in mice via suppressing the TLR4-NF-κB signaling pathway."Inflamm Res. 2018 Dec;67(11):903-911

• 16. [IF=3.225] Fugang Wang et al."Pharmacokinetics, tissue distribution, bioavailability, and excretion of nuciferine, an alkaloid from lotus, in rats by LC/MS/MS."Drug Dev Ind Pharm. 2018;44(9):1557-1562

• 15. [IF=3.512] Thitirat Meelaph et al."Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine."Acs Omega. 2018;3(8):8794–8802

• 14. [IF=5.279] Xianbao Deng et al."Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS."J Agr Food Chem. 2016;64(5):1130–1136

• 13. [IF=6.558] Lei Zhang et al."Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves."Anal Chim Acta. 2017 May;967:52

• 12. Zhang, Lei, et al. "Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves." Analytica chimica acta 967 (2017): 5

• 11. Zhang, Lei, et al. "Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves." Analytica chimica acta 967 (2017): 5

• 10. Chen, X., Zheng, X., Zhang, M. et al. Nuciferine alleviates LPS-induced mastitis in mice via suppressing the TLR4-NF-κB signaling pathway. Inflamm. Res. 67, 903–911 (2018). https://doi.org/10.1007/s00011-018-1183-2

• 9. Fugang Wang, Juan Cao, Xueqin Hou, Zhiyong Li & Xiaolan Qu (2018) Pharmacokinetics, tissue distribution, bioavailability, and excretion of nuciferine, an alkaloid from lotus, in rats by LC/MS/MS, Drug Development and Industrial Pharmacy, 44:9, 1557-1562, D

• 8. 郑艳艳,李莉,袁晓庆,孔方,刘言娟.响应面法优化蜗牛酶辅助超声提取荷叶总生物碱的工艺研究[J].安徽农业科学,2020,48(21):183-187.

• 7. 陈强,张华,沙玫,刘永静.一测多评法同时测定荷叶中4种生物碱含量[J].福建中医药,2020,51(06):29-32.

• 6. 尹秀文, 侯成波, 陈江鹏,等. 采用在体单向肠灌流模型研究荷叶多成分整体的肠渗透性[J]. 中国中药杂志, 2017, 42(008):1525-1531.

• 5. 李帆. 荷叶碱在青霉菌培养基中抑菌效果的研究[J]. 生物化工, 2018, 4(06):99-101.

• 4. 侯成波, 董月柳, 尹秀文,等. 荷叶多成分整体的肠渗透性研究[J]. 中国中药杂志, 2016, 41(07):1183-1187.

• 3. 吴鹏,李慧芬,张学兰,崔伟亮,王均秀.炒炭对荷叶主要化学成分转化机制的研究[J].中成药,2015,37(08):1767-1770.

• 2. 李梦杰 刘苏珍 周斌 等. RP-HPLC法同时测定荷叶颗粒中3种有效成分的含量[J]. 中国药房 2016(18期):2532-2534.

• 1. 梦杰 刘苏珍 周斌 崔小弟 陈振华.HPLC法同时测定荷叶中的荷叶碱、芦丁、槲皮素[J].中成药 2016 38(01):111-114.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *