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  1. 首页 > 标准品 > 中药标准品 > 生物碱 > 胡椒碱

胡椒碱

    
分析标准品,HPLC≥98%

Piperine

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源叶
B20516 一键复制产品信息
94-62-2
C17H19NO3
285.34
MFCD00005839
货号 规格 价格 上海 北京 珠海 武汉 购买数量
B20516-20mg
 分析标准品,HPLC≥98%

￥80.00

 >10 10 - 1
B20516-1g
 分析标准品,HPLC≥98%

￥1000.00

 1 - - -
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产品介绍 参考文献(23篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Piperine是从胡椒中分离的天然生物碱，可以抑制P-glycoprotein and CYP3A4的活性，在HeLa细胞中的IC50值为61.94±0.054 μg/mL。

SMILES： O=C(N1CCCCC1)/C=C/C=C/C2=CC=C(OCO3)C3=C2
熔点： 131-135°C(lit.)
沸点： 498.524°C at 760 mmHg
外观： 白色晶体粉末
溶解性： DMSO  :  50  mg/mL  (175.23  mM;  Need  ultrasonic)
敏感性： 对光,湿度,空气敏感
储存条件： 2-8℃
注意： 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(23篇)

23. [IF=8.3] Shufang Li et al."Daphnetin as a novel polyphosphate kinase inhibitor to combat Salmonella infection."PHYTOMEDICINE.2025 Nov;148:157278 22. [IF=3] Liting Liu et al."Elucidation of anti-SARS-CoV-2 and anti-inflammatory bioactives in Qingyan Dropping Pills via integrated in silico screening and bioactivity validation."Frontiers in Medicine.2025 Nov;12: 21. [IF=8.2] Xinyi Wang et al."A comprehensive study on the effects of drying methods on the color, structure, flavor, and nutritional properties of green peppers (Piper nigrum L.)."Food Chemistry-X.2025 Oct;:103183 20. [IF=7.7] Jingyan Zhao et al."Dietary antioxidants alleviate antibiotic-induced mitochondrial dysfunction through protein kinase AMP-activated alpha (AMPKα) and nuclear factor, erythroid 2 like 2 (NRF2) pathway interaction."BRITISH JOURNAL OF PHARMACOLOGY.2025 Sep; 19. [IF=6.3] Yeye Hu et al."Piperine Improves DSS-Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota."PHYTOTHERAPY RESEARCH.2025 Jun;:
18. [IF=4.9] Dongyan Guan et al."The Extract of Piper nigrum Improves the Cognitive Impairment and Mood in Sleep-Deprived Mice Through the JAK1/STAT3 Signalling Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(5):1842 17. [IF=8.2] Kangyun Zhao et al."Investigation of the formation mechanism of the pepper starch-piperine complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;268:131777 16. [IF=5.8] Chang Yang et al."Umbilical therapy for promoting transdermal delivery of topical formulations: Enhanced effect and underlying mechanism."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Mar;652:123834 15. [IF=6.51] Jiawei Han et al."Mechanistic insight into gel formation of co-amorphous resveratrol and piperine during dissolution process."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Mar;634:122644 14. [IF=3.756] Jiawei Han et al."Self-gelation involved in the transformation of resveratrol and piperine from a co-amorphous system into a co-crystal system."CRYSTENGCOMM.2022 Jul;: 13. [IF=7.419] Baoyi Chen et al."Protective effect of oxyberberine against acute lung injury in mice via inhibiting RhoA/ROCK signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Sep;153:113307 12. [IF=6.321] Yanjie Liu et al."Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer."Pharmaceutics. 2022 Jan;14(1):94 11. [IF=3.779] Xingming Hou et al."Natural Piperine Improves Lipid Metabolic Profile of High-Fat Diet-Fed Mice by Upregulating SR-B1 and ABCG8 Transporters."J Nat Prod. 2021;84(2):373–381 10. [IF=6.023] Maiquan Li et al."Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758 9. [IF=2.419] Tingting Gao et al."Characterization of piperine metabolites in rats by ultra-high-performance liquid chromatography with electrospray ionization quadruple time-of-flight tandem mass spectrometry."Rapid Commun Mass Sp. 2017 Jun;31(11):901-910 8. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664 7. [IF=5.875] Ruoning Wang et al."Involvement of metabolism-permeability in enhancing the oral bioavailability of curcumin in excipient-free solid dispersions co-formed with piperine."Int J Pharmaceut. 2019 Apr;561:9 6. Gao, Tingting, et al. "Characterization of piperine metabolites in rats by ultra‐high‐performance liquid chromatography with electrospray ionization quadruple time‐of‐flight tandem mass spectrometry." Rapid Communications in Mass Spectrometry 31.11 (2017): 5. 陆昕怡, 韩加伟, 李文,等. 姜黄素/胡椒碱固体分散体的制备及体外评价[J]. 现代中药研究与实践, 2018, 032(003):49-53. 4. 黄容, 陆昕怡, 韩加伟,等. 姜黄素-胡椒碱固体分散体的制备与生物利用度研究. 中草药. 3. 陈永昆, 姜亭亭, 吉世松,等. 胡椒碱联合硝苯地平对家兔血压的影响[J]. 临床医学研究与实践, 2017, 2(033):10-11. 2. 宋思维, 唐艳红. 胡椒碱对缺氧复氧心肌细胞的保护作用及机制研究[J]. 岭南心血管病杂志, 2019, 25(01):113-118. 1. 严玉玲, 郭焰, 豆一玲. 胡椒碱分离纯化工艺的研究[J]. 中国农业信息, 2015(17):165.

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摩尔浓度计算器

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