货号	规格	价格	上海	北京	武汉	南京	购买数量
B27465-100mg	分析标准品,HPLC≥95%	￥200.00 B27465-100mg ￥200.00 现货	7 1 7	1	-	-

货号

规格

价格

上海

北京

武汉

南京

购买数量

B27465-100mg

分析标准品,HPLC≥95%

￥200.00

产品介绍

Ivermectin (MK-933) 是一种广谱的抗寄生虫药物。Ivermectin (MK-933) 是一种特异性的 Impα/β1 介导的核导入抑制剂，对 HIV-1 和登革热病毒都具有很强的抗病毒活性。Ivermectin (MK-933) 也是 P2X4 和 α7 nAChRs 的正异构效应物。Ivermectin 还可抑制牛疱疹病毒 1 (BoHV-1) 复制并抑制 BoHV-1 DNA 聚合酶的核输入。Ivermectin 是应用于抗 SARS-CoV-2/COVID-19 的候选药物。

SMILES：	CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@@H]3C[C@H]4C[C@@]5(O[C@]([H])(C(C)C)[C@@H](C)CC5)O3)[C@@H](C)/C=C/C=C6CO[C@@]7([H])[C@]6(O)[C@H](C(O4)=O)C=C(C)[C@H]7O)C[C@@H]2OC)O[C@@H](C)[C@@H]1O.CO[C@H]8C[C@H](O[C@H]9[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@@H]%10C[C@H]%11C[C@@]%12(O[C@]([H])([C@@H](C)CC)[C@@H](C)CC%12)O%10)[C@@H](C)/C=C/C=C%13CO[C@@]%14([H])[C@]%13(O)[C@H](C(O%11)=O)C=C(C)[C@H]%14O)C[C@@H]9OC)O[C@@H](C)[C@@H]8O
比旋光度：	D +71.5 ± 3° (c = 0.755 in chloroform)
外观：	白色至灰白色固体
溶解性：	DMSO : 250 mg/mL (285.68 mM; Need ultrasonic) H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
敏感性：	远离热，明火和火花
储存条件：	2-8℃
注意：	部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(13篇)

13. [IF=2.9] Anben Li et al."Virtual screening, molecular dynamics simulations, and in vitro analysis of Sophora flavescens-derived aloperine against Haemonchus contortus."Frontiers in Veterinary Science.2025 Jun;12: 12. [IF=2] Cuifang Gu et al."Ivermectin induces oxidative stress and mitochondrial damage in Haemonchus contortus."VETERINARY PARASITOLOGY.2024 Nov;:110352 11. [IF=4.7] Tengfei Xiong et al."Functional characterization of Helicoverpa assulta CYP6B6 in insecticide metabolism."PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY".2024 May;201:105857 10. [IF=6.8] Zhanfei Ma et al."A comprehensive study on the ecotoxicity of ivermectin to earthworms (Eisenia fetida)."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2023 Dec;268:115709 9. [IF=9.231] Zhaoyuan He et al."Simultaneous quantitative determination of residues of abamectin, ivermectin, albendazole and its three metabolites in beef and chicken by HPLC-PDA."FOOD CHEMISTRY.2023 Sep;421:136168

8. [IF=5.724] Xiao Yang et al."Sulfoxide-Containing Bisabolane Sesquiterpenoids with Antimicrobial and Nematicidal Activities from the Marine-Derived Fungus Aspergillus sydowii LW09."Journal of Fungi.2023 Mar;9(3):347 7. [IF=1.567] Ziyong Xu et al."Ivermectin induces chicken BCRP/ABCG2 expression and function: Involvement of CXR signaling pathway and mRNA stabilization."JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.2022 Aug;: 6. [IF=7.658] Xuan Zhang et al."Inhibition of TMEM16A Ca2+-activated Cl− channels by avermectins is essential for their anticancer effects."Pharmacol Res. 2020 Jun;156:104763 5. [IF=10.479] Xiao-Fei Shang et al."A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation."J Adv Res. 2020 Dec;: 4. [IF=2.738] Xiao-Fei Shang et al."Acaricidal activity and enzyme inhibitory activity of active compounds of essential oils against Psoroptes cuniculi."Vet Parasitol. 2019 Mar;267:54 3. Shang, Xiao-Fei, et al. "Application of sustainable natural resources in agriculture: Acaricidal and enzyme inhibitory activities of naphthoquinones and their analogs against Psoroptes cuniculi." Scientific reports 8.1 (2018): 1-9.https://doi.org/10.1038/s 2. Xiao-Fei Shang, Li-Xia Dai, Ying-Qian Liu, Zhong-Min Zhao, Jun-Cai Li, Guan-Zhou Yang, Cheng-Jie Yang, Acaricidal activity and enzyme inhibitory activity of active compounds of essential oils against Psoroptes cuniculi, Veterinary Parasitology, Volume 267, 1. Xiao-Fei Shang, Li-Xia Dai, Chen-Jie Yang, Xiao Guo, Ying-Qian Liu, Xiao-Lou Miao, Ji-Yu Zhang, A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation, Journal of Advanced Research, 2020, , ISSN 2090-123

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