| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|
S80548-2mg |
99.50% | ￥200.00 |
7 | - | - | - |
|
S80548-5mg |
99.50% | ￥290.00 |
9 | - | - | - |
|
S80548-10mg |
99.50% | ￥470.00 |
>10 | - | - | - |
|
S80548-25mg |
99.50% | ￥970.00 |
5 | - | - | - |
|
S80548-100mg |
99.50% | ￥2400.00 |
>10 | 2 | - | - |
|
S80548-200mg |
≥98% | ￥3600.00 |
货期：2-3天 | - | - | - |
|
S80548-1g |
≥98% | ￥9600.00 |
货期：2-3天 | - | - | - |
|
| 产品描述： | Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Parasite;Chloride Channel;P-glycoprotein;Bacterial;Chloridechannel;P-gp;Parasite | ||||||||||||||||||||
| 体内研究： | A single administration of 6 mg/kg topical Selamectin given every two months could effectively prevent B. malayi infection in cats. Application of topical Selamectin twice a year could block circulating microfilariae | ||||||||||||||||||||
| 参考文献： | 1. Patsharaporn T Sarasombath, et al. First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions. Parasitol Res. 2019 Apr;118(4):1289-1297. 2. J Griffin, et al. Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein. J Vet Pharmacol Ther. 2005 Jun;28(3):257-65. | ||||||||||||||||||||
| 溶解性： | DMSO : ≥ 100 mg/mL (129.88 mM) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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营业执照(三证合一)
北京