| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S80606-1mg |
99.68% | ￥196.00 | 10 | - | - | - |
|
S80606-5mg |
99.68% | ￥382.00 | 5 | - | - | - |
|
S80606-10mg |
99.68% | ￥578.00 | 4 | - | - | - |
|
S80606-25mg |
99.68% | ￥1190.00 | 7 | - | - | - |
|
S80606-50mg |
99.68% | ￥1680.00 | 4 | - | - | - |
|
S80606-100mg |
99.68% | ￥3230.00 | 4 | - | - | - |
|
| 产品描述： | P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's disease | ||||||||||||||||||||
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| 体内研究： | P7C3 (20 mg/kg/d; i.p.; twice daily; for 21 days ) inhibits microglial activation and microglia-mediated dopaminergic (DA) neuronal loss in vivo | ||||||||||||||||||||
| 参考文献： | 1. Pieper AA et al. Discovery of a proneurogenic, neuroprotective chemical. Cell. 2010 Jul 9;142(1):39-51. 2. Pieper AA et al. P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. Chem Soc Rev. 2014 Oct 7;43(19):6716-26. 3. Chao Gu , et al. P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo. Front Cell Neurosci. 2018; 12: 400. 4. Blaya MO, Wasserman JM, Pieper AA, Sick TJ, Bramlett HM, Dietrich WD. Neurotherapeutic capacity of P7C3 agents for the treatment of Traumatic Brain Injury. Neuropharmacology. 2019;145(Pt B):268-282. | ||||||||||||||||||||
| 溶解性： | DMSO : ≥ 33 mg/mL (69.59 mM) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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