| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S80872-5mg |
99.8% | ￥40.00 | 10 | - | - | - |
|
S80872-10mg |
99.8% | ￥50.00 | 9 | - | - | - |
|
S80872-100mg |
99.8% | ￥240.00 | 4 | - | - | - |
|
S80872-250mg |
99.8% | ￥490.00 | 4 | - | - | - |
|
S80872-1g |
99.8% | ￥1200.00 | 3 | - | - | - |
|
Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia
| 产品描述： | Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Progesterone Receptor;Apoptosis;Estrogen/progestogenReceptor;ProgesteroneReceptor;Autophagy | ||||||||||||||||||||
| 体内研究： | Dienogest (1 mg/kg; p.o.; once daily for 14 days) regulates angiogenesis in ectopic endometrial lesions in rat endometrial autograft model | ||||||||||||||||||||
| 参考文献： | 1. Shimizu Y, et al. Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system. Steroids. 2011 Jan;76(1-2):60-7. 2. Katayama H, et al. Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model. Hum Reprod. 2010 Nov;25(11):2851-8. | ||||||||||||||||||||
| 溶解性： | DMSO : 25 mg/mL (80.28 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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北京