货号	规格	价格	上海	北京	珠海	武汉
S80944-5mg	98.20%	￥60.00 S80944-5mg ￥60.00 现货	97418 >10	-	-	-
S80944-10mg	98.20%	￥95.00 S80944-10mg ￥95.00 现货	48719 >10	-	-	-
S80944-50mg	98.20%	￥102.00 S80944-50mg ￥102.00 现货	9759 >10	-	-	-
S80944-250mg	98.20%	￥305.00 S80944-250mg ￥305.00 现货	1967 >10	-	-	-
S80944-1g	98.20%	￥820.00 S80944-1g ￥820.00 现货	492 >10	-	-	-

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产品描述：

Azithromycin A is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.

靶点：

Antibacterial;Antibiotic

细胞实验：

THP-1 cells (106 cells in 1 mL RPMI medium, without antibiotics, growth factors or serum) are seeded in each well of 24-well plates and allowed to settle for 1 hour. Next, 50 μL of the test compound is added followed by 50 μL of LPS (final concentration of 10 μg/mL). After 24h (37°C and 5% CO2) the supernatants and cell pellets are collected (1200 rpm, 5 min). THP-1 cell viability is tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). MTT is dissolved at 2 mg/mL in PBS and aliquots are stored at -20°C. The MTT assay is performed according to the suppliers instructions. Absorbance of MTT converted into formazan is measured at a wavelength of 570 nm with background subtraction at 630 nm.

参考文献：

1.Noedl H, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):651-6.

溶解性：

DMSO:10 mM

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.361 ml	6.803 ml	13.606 ml
5 mM	0.272 ml	1.361 ml	2.721 ml
10 mM	0.136 ml	0.68 ml	1.361 ml
50 mM	0.027 ml	0.136 ml	0.272 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

Azathramycin

9-Deoxo-9a-aza-9a-homo Erythromycin A (Desmethyl Azithromycin)

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)