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• 产品描述： RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively

• 靶点： Others

• 体内研究：
  Oral administration of RR6 in Wistar rats (150-200 g) completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting. RR6 at 3 mg/mL in rats caused a nearly complete inhibition of plasma vanin

• 参考文献：
  1. Jansen PA et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol. 2013 Mar 15;8(3):530-4.

• 溶解性： soluble  in  DMSO

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.409 ml	17.044 ml	34.088 ml
  5 mM	0.682 ml	3.409 ml	6.818 ml
  10 mM	0.341 ml	1.704 ml	3.409 ml
  50 mM	0.068 ml	0.341 ml	0.682 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *