货号	规格	价格	上海	北京	武汉	南京
S83567-5mg	≥98%	￥100.00 S83567-5mg ￥100.00 现货	6 6	-	-	-
S83567-10mg	≥98%	￥150.00 S83567-10mg ￥150.00 现货	7 7	-	-	-
S83567-25mg	≥98%	￥280.00 S83567-25mg ￥280.00 现货	8 8	-	-	-
S83567-100mg	≥98%	￥420.00 S83567-100mg ￥420.00 现货	2 2	-	-	-

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产品描述：

CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI)

靶点：

AMPA receptor;GluR; iGluR

体内研究：

The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.). Animal Model: Male Lister Hooded rats (56-63 postnatal day) Dosage: 5, 10, 20, and 40 mg/kg Administration: Subcutaneously Result: Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes.Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime.

参考文献：

1. Broberg BV, Glenth?j BY, Dias R, et al. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl). 2009 Nov;206(4):631-40.

溶解性：

Soluble in DMSO、H2O

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.144 ml	20.722 ml	41.444 ml
5 mM	0.829 ml	4.144 ml	8.289 ml
10 mM	0.414 ml	2.072 ml	4.144 ml
50 mM	0.083 ml	0.414 ml	0.829 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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