S87857 |
Compound 3A |
源叶(MedMol) | 98% |
- 产品描述: Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
- 靶点: DNA/RNA Synthesis
- 体内研究: Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase. Corynoxine significantly decreased locomotor activity after oral administration to mice
- 参考文献:
1. Sakakibara I, et al. Effect on locomotion of indole alkaloids from the hooks of uncaria plants. Phytomedicine. 1999 Jul;6(3):163-8. 2. Chen L L , Song J X , Lu J H , et al. Corynoxine, a Natural Autophagy Enhancer, Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway[J]. Journal of Neuroimmune Pharmacology, 2014, 9(3):380-387.
- 溶解性: Soluble in DMSO
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.806 ml 14.028 ml 28.056 ml 5 mM 0.561 ml 2.806 ml 5.611 ml 10 mM 0.281 ml 1.403 ml 2.806 ml 50 mM 0.056 ml 0.281 ml 0.561 ml
- 注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)