S87887 |
CZC-8004 |
| 源叶(MedMol) | 97% |
- 产品描述： CZC-8004 (CZC-00008004), an aminopyrimidine, is a pan-kinase inhibitor. CZC-8004 can bind a range of tyrosine kinases, including EGFR and VEGFR2 with IC50 values of 650 and 437 nM, respectively
- 靶点： IC50: 650 nM (EGFR) and 437 nM (VEGFR2)
- 参考文献：
1. Ying ZD, et, al. Integrated in silico-in vitro analysis of systematic kinase gatekeeper mutation effects on pan-kinase inhibitors in targeted liver cancer therapy. J Chin Chem Soc. 2020 Oct 29;1-10. 2. Deane FM, et, al. FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification. ACS Omega. 2017 Jul 31;2(7):3828-3838. 3. Hubbard RD, et, al. Advances towards the development of ATP-competitive small-molecule inhibitors of the insulin-like growth factor receptor (IGF-IR). ChemMedChem. 2007 Jan;2(1):41-6.
- 溶解性： Soluble in DMSO
- 保存条件： -20℃
- 配置溶液浓度参考：
1mg 5mg 10mg 1 mM 3.233 ml 16.163 ml 32.327 ml 5 mM 0.647 ml 3.233 ml 6.465 ml 10 mM 0.323 ml 1.616 ml 3.233 ml 50 mM 0.065 ml 0.323 ml 0.647 ml
- 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)
