货号	规格	价格	上海	北京	武汉	南京
S80027-1mg	99.8%	￥112.00 S80027-1mg ￥112.00 现货	9 9	-	-	-
S80027-5mg	99.8%	￥192.00 S80027-5mg ￥192.00 现货	5 5	-	-	-
S80027-10mg	99.8%	￥360.00 S80027-10mg ￥360.00 现货	3 3	-	-	-
S80027-25mg	99.8%	￥784.00 S80027-25mg ￥784.00 现货	7 7	-	-	-
S80027-50mg	99.8%	￥1440.00 S80027-50mg ￥1440.00 现货	5 5	-	-	-
S80027-100mg	≥99%	￥2400.00 S80027-100mg ￥2400.00 2-3天	0 货期：2-3天	-	-	-

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产品介绍

SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity

产品描述：

SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity

靶点：

c-Met/HGFR;Raf;p38MAPK;c-Met/HGFR;Bcr-Abl

体内研究：

SGX523 exhibits antitumor activity in vivo. SGX523 inhibits MET-dependent tumor growth

参考文献：

1. Buchanan SG, et al. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol Cancer Ther, 2009, 8(12), 3181-3190.

溶解性：

DMSO : 30 mg/mL (83.47 mM; Need ultrasonic)

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.782 ml	13.911 ml	27.823 ml
5 mM	0.556 ml	2.782 ml	5.565 ml
10 mM	0.278 ml	1.391 ml	2.782 ml
50 mM	0.056 ml	0.278 ml	0.556 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

SGX-523