94. [IF=6] Liu Zhuo et al."Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome."MOLECULAR MEDICINE.2025 Dec;31(1):1-12 93. [IF=1.8] Shu Lianghui et al."Suyin Detoxification Prescription Regulates the Klotho and ERK/NF-κB Signaling Pathways to Alleviate Renal Injury."CELL BIOCHEMISTRY AND BIOPHYSICS.2025 Feb;:1-16 92. [IF=4.4] Tang Lili et al."Combination of Youhua Kuijie Prescription and sulfasalazine can alleviate experimental colitis via IL-6/JAK2/STAT3 pathway."Frontiers in Pharmacology.2024 Sep;15: 91. [IF=4.8] Qiuping Xiao et al."Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance."INTERNATIONAL IMMUNOPHARMACOLOGY.2024 90. [IF=5.1] Jing-Qun Liu et al."Apigenin ameliorates lupus nephritis by inhibiting SAT3 signaling in CD8+T cells."Food & Function.2024 Sep;: 89. [IF=4.8] Yan Chen et al."Targeting RhoA Expression with Formononetin and Salvianolic acid B to Mitigate Pancreatic Cancer-Associated Endothelial Cells Changes."JOURNAL OF ETHNOPHARMACOLOGY.2024 Aug;:118711 88. [IF=8.5] Xiaonan Zhang et al."Physicochemical properties and in vitro release of formononetin nano-particles by ultrasonic probe-assisted precipitation in four polar organic solvents."FOOD CHEMISTRY.2024 Dec;461:140918 87. [IF=1.3] Hong-Ping Wang et al."Screening of potential α-glucosidase inhibitors from astragalus membranaceus by affinity ultrafiltration screening coupled with UPLC-ESI-Orbitrap-MS method."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 86. [IF=3.3] Liu Chun et al."Comparative analysis of lipid and flavonoid biosynthesis between Pongamia and soybean seeds: genomic, transcriptional, and metabolic perspectives."Biotechnology for Biofuels and Bioproducts.2024 Dec;17(1):1-16 85. [IF=3.4] Xianhui Zheng et al."Metabolite Profiling Analysis of the Tongmai Sini Decoction in Rats after Oral Administration through UHPLC-Q-Exactive-MS/MS."Metabolites.2024 Jun;14(6):333 84. [IF=3.9] Jiawei Li et al."Therapeutic targets of formononetin for treating prostate cancer at the single-cell level."Aging-US.2024 Jun 30; 16(12): 10380–10401 83. [IF=6.7] Ruiqian Sun et al."Astragali Radix-Curcumae Rhizoma herb pair reduces the stemness of colorectal cancer cells through HIF-2α/β-catenin pathway."PHYTOMEDICINE.2024 Sep;132:155824 82. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal 81. [IF=3.4] De-Jian Chen et al."Chemical profiling of Zhi-Ke-Bao pills and its potential mechanism against cough by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and network pharmacology."JOURNAL OF PHARMACEUTICAL 80. [IF=5.4] Weiliang Fu et al."Network pharmacology combined with affinity ultrafiltration to elucidate the potential compounds of Shaoyao Gancao Fuzi Decoction for the treatment of rheumatoid arthritis."JOURNAL OF ETHNOPHARMACOLOGY".2024 Aug;330:118268 79. [IF=1.8] Xiaofeng Li et al."Pharmacokinetic study of multicomponent in Hong-Hua-Xiao-Yao tablet."BIOMEDICAL CHROMATOGRAPHY".2024 Mar;:e5830 78. [IF=4.9] Lan Huixuan et al."Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway."Chinese Medicine".2024 Dec;19(1):1-12 77. [IF=1.1] Xudong Luo et al."Development and validation of a simple ultra-high-performance-tandem mass spectrometry method for the simultaneous determination of five bioactive components in rat plasma of Hedysari Radix."Separation Science Plus".2024 Feb;:2300219 76. [IF=3.4] Xinlin Chen et al."Paper-based ligand fishing method for rapid screening and real-time capturing of α-glucosidase inhibitors from the Chinese herbs."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS".2024 May;242:116037 75. [IF=5.4] Hui Ren et al."Integrated serum metabolomics and network pharmacology analysis on the bioactive metabolites and mechanism exploration of Bufei huoxue capsule on chronic obstructive pulmonary disease rats."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;324:117816 74. [IF=5.4] Wenjuan Ma et al."Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117752 73. [IF=5.4] Xinxin Wu et al."The therapeutic efficacy and mechanism action of Si Cao formula in the treatment of psoriasis: A pilot clinical investigation and animal validation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117662 72. [IF=5.6] Di Zhou et al."Establishment of a multicomponent quality control method and the transfer characteristics of five markers from Qidongning Formula to rat tissues by HPLC-QQQ-MS/MS."Frontiers in Pharmacology.2023; 14: 1310266 71. [IF=3.8] Dongli Li et al."Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway."PHARMACEUTICAL BIOLOGY.2023;61(1):1041-1053 70. [IF=1.7] Zhouyi Zhang et al."Revealing the differences in phenolics in different parts of Taraxacum mongolicum using UPLC-MS/MS."Phytochemistry Letters.2023 Aug;56:13 69. [IF=3.1] Yanmin Wang et al."Study on the dynamic metabolic characteristic of main active ingredients in Danggui Buxue Decoction by liquid chromatography-tandem mass spectrometry based on in situ sequential metabolism strategy."JOURNAL OF SEPARATION SCIENCE.2023 Ju 68. [IF=6.1] Huanhuan Zhou et al."Comparative transcriptomic analysis and mechanistic characterization revealed the use of formononetin for bladder cancer treatment."Food & Function.2023 Jun;: 67. [IF=3.776] Lele Zhang et al."Integration of UHPLC/Q-OrbitrapMS-based metabolomics and activities evaluation to rapidly explore the anti-inflammatory components from lasianthus.."Heliyon.2023 May;9(6):e16117-e16117 66. [IF=6.449] Yuanyue Wang et al."A novel flavonoid prenyltransferase gene PcPT11 with broad substrate promiscuity in Psoralea corylifolia L.."INDUSTRIAL CROPS AND PRODUCTS.2023 Sep;199:116746 65. [IF=3.614] Shu-Yun Yang et al."An integrated approach of HPLC-MS-based chemical profiling, network pharmacology, and molecular docking to reveal the potential mechanisms of Qishen Gubiao Granules for treating COVID-19."JOURNAL OF SEPARATION SCIENCE.2023 Mar;:2200953 64. [IF=4.927] Chenghui Pan et al."The Fate and Intermediary Metabolism of Soyasapogenol in the Rat."MOLECULES.2023 Jan;28(1):284 63. [IF=6.449] Yanmei Li et al."Regional variations and plant compartments shape the community structures of the endophytic microbiome and secondary metabolites of Astragalus mongholicus."INDUSTRIAL CROPS AND PRODUCTS.2023 Feb;192:116037 62. [IF=6.656] Ying Yang et al."Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial polarization."PHYTOMEDICINE.2022 Dec;:154602 61. [IF=6.656] Chong Chen et al."Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling."PHYTOMEDICINE.2022 Nov;:154546 60. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380 59. [IF=3.571] Yuhao Zhang et al."A novel strategy integrating gas phase fractionation with staggered mass range and LC-MS/MS molecular network for comprehensive metabolites profiling of Gui Ling Ji in rats."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Jan;222 58. [IF=5.988] Jun Li et al."Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach.."Frontiers in Pharmacology.2022 Oct;13:999950-999950 57. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199 56. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747 55. [IF=9.231] Tong Zhao et al."Identification of characteristic markers for monofloral honey of Astragalus membranaceus var. mongholicus Hsiao: A combined untargeted and targeted MS-based study."FOOD CHEMISTRY.2022 Sep;:134312 54. [IF=1.978] Chen Ming-jun et al."Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3."Chin J Integr Med. 2022 Apr;:1-10 53. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 52. [IF=5.34] Lei Jin et al."Simultaneous optimization of the extraction process of Yangyin Yiqi Huoxue prescription with natural deep eutectic solvents for optimal extraction yield and antioxidant activity: A comparative study of two models."PHYTOMEDICINE. 2022 Jul;102 51. [IF=3.645] Jingbin Chen et al.Screening for potential quality markers of Callerya nitida var. hirsutissima. Z.Wei based on components profile, pharmacokinetics, and anti-inflammatory study.Journal Of Separation Science.2021 Nov 02 50. [IF=2.629] Li Tingting et al."Quality Assessment of Licorice Based on Quantitative Analysis of Multicomponents by Single Marker Combined with HPLC Fingerprint."Evid-Based Compl Alt. 2021;2021:8834826 49. [IF=2.629] Wang Lingdi et al."Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency."Evid-Based Compl Alt. 2021;2021:6614302 48. [IF=2.633] Ruoke Ma et al."Variation of Chemical Components in Sapwood, Transition Zone, and Heartwood of Dalbergia odorifera and Its Relationship with Heartwood Formation."Forests. 2021 May;12(5):577 47. [IF=2.984] Chenkai Wang et al."Comparative transcriptome analysis of roots, stems, and leaves of Pueraria lobata (Willd.) Ohwi: identification of genes involved in isoflavonoid biosynthesis."Peerj. 2021 Feb;9:e10885 46. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 45. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556 44. [IF=3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia."J Ethnopharmacol. 2020 Apr;252:112573 43. [IF=4.142] Hu Guizhou et al."An integrated strategy for the identification and screening of anti-allergy components from natural products based on calcium fluctuations and cell extraction coupled with HPLC–Q–TOF–MS."Anal Bioanal Chem. 2021 Oct;413(25):6253-6266 42. [IF=4.225] Zhang Wei et al."Five Active Components Compatibility of Astragali Radix and Angelicae Sinensis Radix Protect Hematopoietic Function Against Cyclophosphamide-Induced Injury in Mice and t-BHP–Induced Injury in HSCs."Front Pharmacol. 2019 Aug;0:936 41. [IF=4.411] Liyu Luo et al."Integrated Phytochemical Analysis Based on UPLC-MS and Network Pharmacology Approaches to Explore the Quality Control Markers for the Quality Assessment of Trifolium pratense L.."Molecules. 2020 Jan;25(17):3787 40. [IF=4.411] Mengyang Hou et al."Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of Flavonoid Profiles by HPLC-PAD."Molecules. 2019 Jan;24(17):3200 39. [IF=4.486] Xin Li et al."Formononetin, J1 and J2 have different effects on endothelial cells via EWSAT1‐TRAF6 and its downstream pathway."J Cell Mol Med. 2020 Jan;24(1):875-885 38. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato 37. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;: 36. [IF=4.879] Yang Liu et al."UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings."Biomolecules. 2020 Apr;10(4):504 35. [IF=5.81] Gu Junfei et al."Standardized Astragalus Mongholicus Bunge-Curcuma Aromatica Salisb. Extract Efficiently Suppresses Colon Cancer Progression Through Gut Microbiota Modification in CT26-Bearing Mice."Front Pharmacol. 2021 Aug;0:2278 34. [IF=8.579] Chuanrui Ma et al."Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE-/- mice."Theranostics. 2020; 10(3): 1090–1106 33. [IF=2.705] Shu Yang et al."Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα."Biochem Bioph Res Co. 2019 May;512:770 32. [IF=3.208] Teng Li et al."Formononetin induces vasorelaxation in rat thoracic aorta via regulation of the PI3K/PTEN/Akt signaling pathway."Drug Des Dev Ther. 2018; 12: 3675–3684 31. [IF=3.361] Taofang Cheng et al."Hybrid multidimensional data acquisition and data processing strategy for comprehensive characterization of known, unknown and isomeric compounds from the compound Dan Zhi Tablet by UPLC-TWIMS-QTOFMS."Rsc Adv. 2019 Mar;9(16):8714-8727 30. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56 29. [IF=3.935] Ziying Liu et al."Promotion of classic neutral bile acids synthesis pathway is responsible for cholesterol-lowing effect of Si-miao-yong-an decoction: Application of LC–MS/MS method to determine 6 major bile acids in rat liver and plasma."J Pharmaceut Bio 28. [IF=3.935] Nan Mi et al."Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis."J Pharmaceut Biomed. 2019 Feb;164:70 27. [IF=4.411] Liangliang Liu et al."Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS."Molecules. 2016 Nov;21(11):1471 26. [IF=4.411] Jing Zhou et al."Simultaneous Optimization for Ultrasound-Assisted Extraction and Antioxidant Activity of Flavonoids from Sophora flavescens Using Response Surface Methodology."Molecules. 2019 Jan;24(1):112 25. [IF=4.522] Wei Hu et al."In vitro and in vivo studies of antiosteosarcoma activities of formononetin."J Cell Physiol. 2019 Oct;234(10):17305-17313 24. [IF=4.759] Yuping Zhang et al."On-line surface plasmon resonance-high performance liquid chromatography–tandem mass spectrometry for analysis of human serum albumin binders from Radix Astragali."J Chromatogr A. 2013 Jun;1293:92 23. Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https://doi.org/10.1016/ 22. Mi, Nan, et al. "Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: an integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis." Journal of pharmaceutical and biomedical analysis 164 (2019): 70-85 21. Wang, Lingdi, et al. "Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency." Evidence-Based Complementary and Alternative Medicine 2021 (2021).https://doi.org/10.1155/2021/6614302 20. Wang, Qian, et al. "Identification and pharmacokinetics of multiple constituents in rat plasma after oral administration of Yinchenzhufu decoction." Journal of ethnopharmacology 153.3 (2014): 714-724.https://doi.org/10.1016/j.jep.2014.03.039 19. Peng-Peng, L. I. U., et al. "Metabolomics analysis and rapid identification of changes in chemical ingredients in crude and processed Astragali Radix by UPLC-QTOF-MS combined with novel informatics UNIFI platform." Chinese journal of natural medicines 16.9 18. 毛文点,庹玲玲,齐文续,苏睿智,邓常清,邹龙.黄芪-当归不同配伍对其6种主要有效成分溶出的影响[J].湖南中医药大学学报,2021,41(03):350-354. 17. 冯紫薇. 子洲黄芪饮片质量等级标准研究[D].北京中医药大学,2020. 16. 田文仓. 不同生长年限及采收期子洲黄芪鉴别特征及其质量、产量差异分析[D].北京中医药大学,2020. 15. 徐艳阳,赵玉娟,高峰,王二雷,鲁海玲,李雪凤,姜雯雯,陈艳.高效液相色谱法分析中国人参不同部位中多酚类化合物[J].食品科学,2021,42(04):240-246. 14. 常冠华,薄颖异,崔洁,徐露露,赵梓邯,王文全,侯俊玲.基于UPLC-Q-Exactive Orbitrap-MS分析甘草地上部分主要化学成分[J].中国中药杂志,2021,46(06):1449-1459. 13. 孙秀蕊,魏桂杰,王宏雅,赵雯雯,张哲,张婷,魏锋,张玉杰.基于外观性状和内在成分的黄芪药材质量等级评价[J].中国中药杂志,2021,46(04):966-971. 12. 杨雨桐,张卿硕,符韵林,孙静.巴里黄檀心材色素成分及其稳定性和抗氧化性[J].林业科学,2021,57(03):126-134. 11. 勾玲,唐珍,苏春蓝,姚水莲,卢海啸.牛大力标准提取物制备工艺研究[J].海峡药学,2020,32(11):1-3. 10. 余颖, 樊金玲, 程源斌,等. 甘草酸提取废液α-葡萄糖苷酶抑制剂的筛选与鉴定[J]. 食品科学, 2018, 39(13). 9. 李欣, 卓冰雨, 祁晓娟,等. 黄芪异黄酮含量与气候因子的灰色关联度和通径分析[J]. 中国中药杂志 2020年45卷14期, 3407-3413页, MEDLINE ISTIC PKU CSCD CA BP, 2020. 8. 侯美如, 尹珺伊, 王岩,等. 黄芪发酵前后黄酮含量及指纹图谱比较研究[J]. 中国兽药杂志, 2018, v.52(05):52-58. 7. 刘杰 何钢 刘贤桂 等. 人工栽培鸡血藤中五种黄酮类物质含量测定[J]. 分子植物育种 2017 015(009):3832-3837. 6. 尚兴朴,欧阳罗丹,肖苏萍,王继永,高永坚,袁春平,刘畅.黄芪饮片质量评价和分级标准探讨[J].中国现代中药,2020,22(05):772-779. 5. 黎映琼 蔡庆群 苏志强 等. 不同产地黄芪根 茎 叶中4种异黄酮类成分的比较及其聚类分析[J]. 现代中药研究与实践 2020 v.34;No.173(02):69-73. 4. 刘雪 石晓倩 吴晏杰 等. UPLC法同时测定新安名方脑络欣通中5个活性成分的含量[J]. 贵阳中医学院学报 2020年42卷4期 26-31页 ISTIC 2020. 3. 勾玲, 唐珍, 苏春蓝,等. 牛大力黄酮类成分提取条件的优化[J]. 检验检疫学刊, 2020, 030(002):P.78-80. 2. 刘洋, 张鑫, 石秀佳,等. 基于PBPK模型的在体单向肠灌流技术对苷元成分的适用性分析评价[J]. 中国中药杂志, 2019(17):3645-3652. 1. 陆晖 陆瑞勇.HPLC测定玉郎伞中芒柄花素的含量[J].中国民族民间医药 2013 22(18):25-26.