品牌	货号	产品规格	价格(RMB)	库存（上海）	北京	武汉	南京	购买数量
源叶	B21008-20mg	分析标准品,HPLC≥98%	￥100.00元	>10	-	-	4
源叶	B21008-100mg	分析标准品,HPLC≥98%	￥350.00元	>10	-	-	-

产品介绍

Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)

熔点：	150-160℃
比旋光度：	(CHCl3)-121
外观：	白色粉末
溶解性：	Soluble in DMSO、H2O
敏感性：	对光敏感,易吸潮
储存条件：	2-8℃
用途：	Functions by binding to tubulin and arresting cell division at m
注意：	部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(14篇)

14. [IF=5.7] Ziqiao Yuan et al."Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;72(41):22606–22620 13. [IF=6.7] Wen-hui Wu et al."Ginsenoside compound K restrains hepatic fibrotic response by dual-inhibition of GLS1 and LDHA."PHYTOMEDICINE.2024 Nov;:156223 12. [IF=4.5] Mingxue Liu et al."Preparation of combined colchicine with loxoprofen sodium loaded in dissolvable microneedles and its anti-gouty arthritis effect."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2024 Dec;:106471 11. [IF=3.2] Lu Yuan et al."Biosafety and Efficacy Studies of Colchicine-Encapsulated Liposomes for Ocular Inflammatory Diseases."JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.2025 Jan;113(2):e35540 10. [IF=14.3] Jing Yu et al."Activation of Nuclear Receptor CAR: A Pathway to Delay Aging through Enhanced Capacity for Xenobiotic Resistance."Advanced Science.2025 Jan;:2416823

9. [IF=7.9] Tian Lan et al."Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation."PHYTOMEDICINE".2024 Jun;128:155477 8. [IF=6.1] Guangwen Shu et al."Ergothioneine suppresses hepatic stellate cell activation via promoting Foxa3-dependent potentiation of the Hint1/Smad7 cascade and improves CCl4-induced liver fibrosis in mice."Food & Function.2023 Nov;: 7. [IF=3.3] Piao Huiqing et al."Ternary Deep Eutectic Solvents System of Colchicine, 4-Hydroxyacetophenone, and Protocatechuic Acid and Characterization of Transdermal Enhancement Mechanism."AAPS PHARMSCITECH.2023 Dec;24(8):1-15 6. [IF=7.9] Tingting Qin et al."Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis."PHYTOMEDICINE.2023 Sep;118:154971 5. [IF=16.6] Fan Shengjie et al."Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions."Nature Communications.2023 Jun;14(1):1-23 4. [IF=6.51] Meng Chen et al."Deuterated colchicine liposomes based on oligomeric hyaluronic acid modification enhance anti-tumor effect and reduce systemic toxicity."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2022 Dec;:122578 3. [IF=9.229] Qing-Shan Liu et al."Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture."Acs Appl Mater Inter. 2017;9(7):5725–5732 2. 范素芳, 马俊美, 刘茁,等. 高效液相色谱-串联质谱测定食品中15种有毒生物碱[J]. 食品科学, 2018, 39(22):290-295. 1. 李培宁陈秀娟江漪等. 3种化合物在UV诱导下对CHL细胞染色体畸变作用[J]. 日用化学工业 2019 49(006):377-380 387.

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Colchicine