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水飞蓟宾

    
分析标准品,HPLC≥98%

Silibinin

源叶
B21185 一键复制产品信息
22888-70-6
C25H22O10
482.443
MFCD03225424
益肝灵;西利马林;2,3-二氢-3-(4-羟基-3-甲氧基苯基)-2-羟甲基-6-(3,5,7-三羟基-4-氧代苯并吡喃-2-基)苯并二氧六环
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
B21185-20mg
分析标准品,HPLC≥98%

¥80.00

>10 7 3 - 1
B21185-100mg
分析标准品,HPLC≥98%

¥280.00

6 2 - - -
B21185-5g
分析标准品,HPLC≥98%

¥4200.00

货期:2-3天 - - - -
产品介绍 参考文献(32篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Silibinin (Silibinin A) 为抗癌和化疗预防化合物,能抑制细胞增殖和迁移。

SMILES: O=C1[C@H](O)[C@@H](C2=CC=C(O[C@H](CO)[C@@H](C3=CC=C(O)C(OC)=C3)O4)C4=C2)OC5=CC(O)=CC(O)=C15
熔点: 164-174°C
沸点: 793°C at 760mmHg
比旋光度: +8 ~ +12 ° (c=0.21in acetone at 20 °C)
外观: 类白色结晶性粉末
溶解性: DMSO  :  250  mg/mL  (518.20  mM;  Need  ultrasonic)
储存条件: 2-8℃
密度: 1.527
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(32篇)

27. [IF=8.3] Qingmiao Shi, et al. "Immunoregulatory mechanisms underlying vitexin-mediated attenuation of concanavalin A-induced liver injury"PHYTOMEDICINE, 2026 Apr;:158231 26. [IF=2.6] Tao Chen et al."Botrychium ternatum, the Hmong medicinal flora, improves acetaminophen-induced hepatic injury by inhibiting the abnormal activation of the B cell receptor signaling pathway."FITOTERAPIA.2026 Jan;:107096 25. [IF=2.5] Zhe Cheng et al."Integrated serum metabolomics reveal molecular mechanism of Xietu Hemu prescription on metabolic dysfunction-associated steatotic liver disease-related obesity."World Journal of Hepatology.2025 Dec;17(12):113660 24. [IF=5.9] Qingmiao Shi et al."Single-cell transcriptional profiling revealed the protective effects of Buddleoside in sepsis-associated acute liver injury."Frontiers in Immunology.2026 Jan;16: 23. [IF=8.3] Shufang Li et al."Daphnetin as a novel polyphosphate kinase inhibitor to combat Salmonella infection."PHYTOMEDICINE.2025 Nov;148:157278 22. [IF=7.2] Mengyao Wu et al."Multi-omics analysis reveals the anti-obesity and hepatoprotective properties in Termitomyces intermedius extracts."Journal of Future Foods.2025 Jul;: 21. [IF=4.9] Zhiwen Zhang et al."Effect of Particle Size on Physical Properties, Dissolution, In Vitro Antioxidant Activity, and In Vivo Hepatoprotective Properties of Tetrastigma hemsleyanum Diels et Gilg Powders."Pharmaceutics.2024 Nov;16(11):1352 20. [IF=5] Wei Wang et al."Beneficial effects of silibinin on serum lipids, bile acids, and gut microbiota in methionine-choline-deficient diet-induced mice."Frontiers in Nutrition.2023; 10: 1257158 19. [IF=5.9] Xiaomei Zheng et al."Eriodictyol Alleviated LPS/D-GalN-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Cell Apoptosis via PI3K/AKT Signaling Pathway."Nutrients.2023 Jan;15(20):4349 18. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747 17. [IF=3.246] Xu Renjie et al."Fabrication of Stable Apigenin Nanosuspension with PEG 400 as Antisolvent for Enhancing the Solubility and Bioavailability."Aaps Pharmscitech. 2022 Jan;23(1):1-11 16. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 15. [IF=4.268] Jie Chen et al."Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition of NF-κB and MAPK activation."Phytomedicine. 2020 Nov;78:153309 14. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12 13. [IF=1.908] Yan Chen et al."Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers."Xenobiotica. 2019;49(11):1269-1278 12. [IF=2.977] Yan-Jiao Li et al."Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway."Behav Brain Res. 2018 Aug;348:184 11. [IF=4.5] Wang Min et al."Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury."Mol Neurobiol. 2016 Mar;53(2):932-943 10. Li, Fang, et al. "Lactobacillus fermentum HFY06 reduced CCl 4-induced hepatic damage in Kunming mice." RSC Advances 10.1 (2020): 1-9.https://doi.org/10.1039/C9RA08789C 9. Jie Chen, Dong-Li Li, Ling-Na Xie, Yu-ran Ma, Pan-Pan Wu, Chen Li, Wen-Feng Liu, Kun Zhang, Ren-Ping Zhou, Xue-Tao Xu, Xi Zheng, Xia Liu, Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition 8. 秦帅,吴丽丽,秦灵灵,张程斐,吴呦呦,孙伯菊,刘铜华.水飞蓟宾对C2C12细胞胰岛素抵抗的影响及机制研究[J].世界科学技术-中医药现代化,2020,22(10):3450-3455. 7. 张丽芳, 林霞, 冯星海,等. 超声辅助有机溶剂回流提取水飞蓟籽中水飞蓟素工艺的优化[J]. 中成药, 2019, 41(001):185-188. 6. 郑成凤 潘裕添 苑小宁 等. HPLC-UV-MS法对洋蓟中多酚类化合物的分析和鉴定[J]. 漳州师范学院学报(自然科学版) 2013(3):81-87. 5. 仲金秋, 曹玉珠, 徐宏江,等. 甘草酸二铵改善ConA致小鼠肝损伤的作用研究[J]. 天然产物研究与开发, 2018, 30(12):60-68. 4. 张会芳, 杨亚琛, 张久亮,等. 油菜蜂花粉加工副产物多酚对小鼠急性肝损伤的保护作用[J]. 食品安全质量检测学报, 2018, v.9(09):59-66. 3. 王立, 薛冰, 刘华石,等. 水飞蓟宾葡甲胺渗透泵片的制备及其释放机制考察[J]. 中国医药工业杂志, 2018. 2. 王立, 杨硕, 马维阳,等. 水飞蓟宾控释制剂的制备及释放机制研究[J]. 中草药, 2015(08):1145-1150. 1. 徐静涵, 薛芸, 王彦,等. 核壳型色谱柱-高效液相色谱法快速分离检测水飞蓟素中7种非对映异构体[J]. 化学与生物工程, 2017, 06(v.33;No.222):69-74.

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摩尔浓度计算器

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