吴茱萸碱

分析标准品,HPLC≥98%

Evodiamine

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品牌：源叶

产品编号：B21315 一键复制产品信息

CAS号：518-17-2

分子式：C₁₉H₁₇N₃O

分子量：303.36

MDL：MFCD06407824

别名：吴茱萸胺

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
B21315-20mg	分析标准品,HPLC≥98%	￥200.00 B21315-20mg ￥200.00 现货	0 9 货期：2-3天	5	1	-	3
B21315-100mg	分析标准品,HPLC≥98%	￥500.00 B21315-100mg ￥500.00 现货	5 5	-	-	-	-

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产品介绍参考文献(30篇) 质检证书(COA) 摩尔浓度计算器相关产品

产品介绍

药理药效：吴茱萸碱有健胃、镇痛、止干呕和止嗳酸等功效;有利尿作用;对大肠杆菌有强力的抑制作用;对猪蛔虫有显著杀虫作用;还有收缩子宫及升压作用。治疗早老性痴呆症及中风有一定疗效。

SMILES：	O=C1C2=CC=CC=C2N(C)[C@](N1CC3)([H])C4=C3C5=CC=CC=C5N4
熔点：	263-265°C
沸点：	575.1°C at 760 mmHg
比旋光度：	D15 +352° (acetone); D +440° (chloroform)
外观：	白色针晶（氯仿）
溶解性：	溶于丙酮，微溶于乙醇、乙醚、氯仿，几乎不溶于水、石油醚、苯
敏感性：	对光敏感
储存条件：	2-8℃
密度：	1.39
注意：	部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(30篇)

30. [IF=11.3] Liping Wang, et al. "Euodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang and evodiamine ameliorate N-methyl-N′-nitro-N-nitrosoguanidine-induced chronic atrophic gastritis in rats via the phosphatidylinositol 3-kinase/protein kinase B/nuclear fa웿Ů 29. [IF=9.8] Yuzhe Yuan, et al. "Comprehensive screening strategy for potentially hazardous plant secondary metabolites in honey using natural deep eutectic solvent extraction combined with LC-MS/MS"FOOD CHEMISTRY, 2026 Apr;508:148563 28. [IF=2.9] Yongqi Peng, et al. "Preparation and evaluation of plumbagin-loaded lipid cubic liquid crystal nano-drug delivery system"PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2026-05-11 27. [IF=4.8] Jianyu Zhang et al."Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport."Frontiers in Pharmacology.2026 Jan;17: 26. [IF=5.7] Zhao Chongjun et al."The conversion of evodiamine-induced hepatotoxicity into a therapeutic effect on colonitis: insight from the liver-gut axis mediated by PPAR/NF-κB/ZO-1/caspase-3 pathway."Chinese Medicine.2025 Dec;20(1):198

25. [IF=8.3] Shufang Li et al."Daphnetin as a novel polyphosphate kinase inhibitor to combat Salmonella infection."PHYTOMEDICINE.2025 Nov;148:157278 24. [IF=8.3] Yunjie Zhao et al."Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy."PHYTOMEDICINE.2025 May;:156866 23. [IF=3.1] Xiaofei Chen et al."Mechanistic insights into Licorice-Evodiae Fructus interaction: UPLC-MS/MS-based hepatotoxic metabolite detection and CYP3A4 regulation study."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2025 Oct;264:116985 22. [IF=6.7] Guoliang Cui et al."Berberine In Combination With Evodiamine Ameliorates Gastroesophageal Reflux Disease Through TAS2R38/TRPV1-Mediated Regulation of MAPK/NF-κB Signaling Pathways and Macrophage Polarization."PHYTOMEDICINE.2024 Nov;:156251 21. [IF=4.8] Yan Wang et al."Activating TRPV1 by evodiamine attenuates atherosclerosis by inhibiting endothelial microparticle release."INTERNATIONAL IMMUNOPHARMACOLOGY.2025 May;155:114657 20. [IF=4.9] Xiaoran Zhao et al."Constructing a hydrogel based on self-assembly properties of glycyrrhizic acid: A drug delivery system with digestive tract responsive."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2024 Sep;697:134497 19. [IF=6.8] Qiqi Fan et al."Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY".2024 Jul;279:116448 18. [IF=4.3] Peng Ting et al."Elucidation of the relationship between evodiamine-induced liver injury and CYP3A4-mediated metabolic activation by UPLC-MS/MS analysis."ANALYTICAL AND BIOANALYTICAL CHEMISTRY.2023 Jul;:1-17 17. [IF=11.072] Qiang Yu et al."A deep eutectic solvent binary-phase system for alkaloid extraction from Chinese herb Evodia lepta residue and its mechanism."Journal of Cleaner Production.2023 Apr;398:136645 16. [IF=2.838] Wang Shuo et al."Toxicity and toxicokinetics of the ethanol extract of Zuojin formula."BMC Complementary Medicine and Therapies.2022 Dec;22(1):1-14 15. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS 14. [IF=4.05] Xingming Hou et al."Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice."J Nat Prod. 2021;XXXX(XXX):XXX-XXX 13. [IF=2.952] Yongfeng Zhang et al."Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects."Mol Med Rep. 2022 May;25(5):1-14 12. [IF=4.432] Zhijun Zhao et al."Identification of evodiamine and rutecarpine as novel TMEM16A inhibitors and their inhibitory effects on peristalsis in isolated Guinea-pig ileum."Eur J Pharmacol. 2021 Oct;908:174340 11. [IF=4.183] Yongfeng Zhang et al."Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis."Int J Mol Sci. 2018 May;19(5):1527 10. Zhang Y, Wang J, Wang C, Li Z, Liu X, Zhang J, Lu J, Wang D. Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis. International Journal of Molecular Sciences. 2018; 19(5):1527. https://doi.org/10.3390/ijm 9. 陈永顺,杨金霞,吴珍.吴茱萸碱水凝胶贴剂的研制及质量评价[J].中国药师,2021,24(03):571-574. 8. 周建新,沈硕,杜茂波,李玉洁,孙奕,何爱萍,姚瑶,王明硕,刘淑芝,尹永芹.基于UPLC-Q-TOF-MS技术和整合药理学方法探索吴茱萸经皮成分及其治疗腹泻的分子机制[J].中国实验方剂学杂志,2021,27(07):112-120. 7. 徐国波,雷丹丹,肖耀华,陈广桂,何迅,廖尚高.良姜胃疡胶囊高效液相色谱特征指纹图谱研究[J].中南药学,2020,18(09):1503-1507. 6. 刘璐,王雪梅,王岩,席红梅,郭建多,黄求进.吴茱萸碱对胶质瘤SHG-44细胞凋亡的促进作用及其机制[J].中国医学科学院学报,2020,42(05):591-595. 5. 张红梅, 李国, 宋龙, et al. 贵州和浙江产吴茱萸指纹图谱分析及含量测定[J]. 中国实验方剂学杂志, 2014, 20(017):69-73. 4. 张红梅李国宋龙等. 吴茱萸与伪品臭辣树果实的生药学鉴定[J]. 中药材 2016(3期):515-518. 3. 曹志杨伊林王穗暖等. 吴茱萸碱对人胶质瘤U251细胞增殖及凋亡影响的研究[J]. 临床神经外科杂志 2014. 2. 顾家毓余丹丹邬瑞光. 吴茱萸碱与脂质体模拟生物膜的相互作用:FTIR和DSC研究[J]. 光谱学与光谱分析 2019 39(006):1757-1762. 1. 张婧怡林淑娴侯化化等. 吴茱萸总碱抑制大鼠左室肥厚及对钙调神经磷酸酶信号通路的影响[J]. 遵义医学院学报 2014 37(002):151-155.

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