43. [IF=6.7] Xin Ye Ji et al."Catalpol alleviates heat stroke-induced liver injury in mice by downregulating the JAK/STAT signaling pathway."PHYTOMEDICINE.2024 Sep;132:155853 42. [IF=5.3] Yuyi Wu et al."A gel plaster in the form of nipple cover: A comfortable and safe transdermal delivery method for mammary hyperplasia."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Sep;662:124500 41. [IF=4.6] Jingjing Yang et al."Exploration of the Dynamic Variations of the Characteristic Constituents and the Degradation Products of Catalpol during the Process of Radix Rehmanniae."MOLECULES".2024 Jan;29(3):705 40. [IF=3.5] Yuanjun Li et al."Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant Rehmannia glutinosa and the Functional Characterization of RgGES Genes."Genes.2024 Feb;15(2):155 39. [IF=7.9] Shuai Chen et al."Catalpol attenuates osteoporosis in ovariectomized rats through promoting osteoclast apoptosis via the Sirt6-ERα-FasL axis."PHYTOMEDICINE.2024 Jan;123:155262 38. [IF=3.9] Ying Zhang et al."Potential benefits of Rehmanniae Radix after ancient rice-steaming process in promotion of antioxidant activity in rats' health."Food Science & Nutrition.2023 Jun;: 37. [IF=7.5] Si Li et al."Catalpol rescues cognitive deficits by attenuating amyloid β plaques and neuroinflammation."BIOMEDICINE & PHARMACOTHERAPY.2023 Sep;165:115026 36. [IF=2.65] Minghui Wu et al."Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice."Evidence-based Complementary and Alternative Medicine.2022 Nov 25;2022:7074157 35. [IF=3.978] Du Jikun et al."Catalpol Ameliorates Neurotoxicity in N2a/APP695swe Cells and APP/PS1 Transgenic Mice."NEUROTOXICITY RESEARCH.2022 Jun;:1-12 34. [IF=2.759] Yuxi Di et al."Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels."Yonsei Med J. 2022 Jan; 63(1): 56–65 33. [IF=1.982] Lili Song et al."Metabolism of Du Zhong Formula in rats using UPLC-Q-TOF/MS."J Mass Spectrom. 2022 Jan;57(1):e4795 32. [IF=2.984] Linluo Zhang et al."Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway."Peerj. 2022 Jan;10:e12759 31. [IF=3.935] Yong-Sheng Wu et al."Chemical profiling of Callicarpa nudiflora and its effective compounds identification by compound-target network analysis."J Pharmaceut Biomed. 2020 Apr;182:113110 30. [IF=4.162] Weixin Hou et al."The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats."Drug Des Dev Ther. 2021; 15: 3845–3862 29. [IF=4.183] Wan Gong et al."Rehmannia glutinosa Libosch Extracts Prevent Bone Loss and Architectural Deterioration and Enhance Osteoblastic Bone Formation by Regulating the IGF-1/PI3K/mTOR Pathway in Streptozotocin-Induced Diabetic Rats."Int J Mol Sci. 2019 Jan;20(16 28. [IF=4.225] Yang Fan et al."Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways."Front Pharmacol. 2021 Jan;11:2472 27. [IF=4.225] Yang Chunjing et al."Neuroprotective Effect of Catalpol via Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms."Front Pharmacol. 2020 May;11:690 26. [IF=4.36] Chenglin Song et al."Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23/Th17 cell axis."J Ethnopharmacol. 2021 Dec;281:114571 25. [IF=6.6] Longtai You et al."Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway."Cells-Basel. 2021 Oct;10(10):2635 24. [IF=2.1] Yun Han et al."Antiangiogenic effects of catalpol on rat corneal neovascularization."Mol Med Rep. 2018 Feb;17(2):2187-2194 23. [IF=2.479] Yang Tao et al."Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice."Bmc Complem Altern M. 2017 Dec;17(1):1-15 22. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696 21. [IF=4.411] Wei Wang et al."In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."Molecules. 2016 May;21(5):597 20. [IF=4.545] Chao Lin et al."Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor."Biomed Pharmacother. 2017 May;89:973 19. [IF=4.759] Mingzhen He et al."Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."J C 18. [IF=6.799] Yun Tang et al."Quantifying orientational regeneration of injured neurons by natural product concentration gradients in a 3D microfluidic device."Lab Chip. 2018 Mar;18(6):971-978 17. Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism." Molecules 21.5 (2016): 597.https://doi.org/10.3390/molecules21050597 16. He, Mingzhen, et al. "Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv." 15. Lin, Chao, et al. "Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor." Biomedicine & Pharmacotherapy 89 (2017): 973-982.https://doi.org/10.1016/j.biopha.2017.02.069 14. Yang, Tao, et al. "Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice." BMC complementary and alternative medicine 17.1 (2017): 1-15.https://doi.org/10.1186/s12906-017 13. Yang, Chunjing, et al. "Neuroprotective effect of catalpol via anti-oxidative, anti-inflammatory, and anti-apoptotic mechanisms." Frontiers in Pharmacology 11 (2020): 690.https://doi.org/10.3389/fphar.2020.00690 12. 化宝军,赵世莉,苏妍妍,杨椹.梓醇对急性肾损伤大鼠TLR4/NF-κB通路及肾小球内皮损伤的影响[J].中国中西医结合肾病杂志,2020,21(12):1042-1046+1137. 11. 李尽文,宋代博,李苑华,麦键城,刘咏倩,李莉.梓醇对宫颈癌HeLa细胞增殖及凋亡作用的研究[J].山东化工,2020,49(17):43-45. 10. 陶玉菡,许惠琴,李莉,农伟虎,李伟.生地、山茱萸抑制和清除糖基化产物的效应成分研究[J].中药药理与临床,2013,29(04):30-33. 9. 周炳文, 钟晓明, 黄真. 玄参环烯醚萜苷热回流提取工艺的优化[J]. 中成药, 2018, 040(006):1292-1297. 8. 蒙雄裕, 徐良, 李华强,等. 用RP-HPLC法测定天目地黄中梓醇和毛蕊花糖苷的含量[J]. 药学服务与研究, 2015, 15(004):273-276. 7. 陆春红, 许惠琴, 刘凯,等. 生地环烯醚萜苷类成分对AGEs损伤HUVEC的保护作用[J]. 南京中医药大学学报, 2015, 31(001):55-59. 6. 李强, 胡晶红, 张永清,等. 晒干与烘干生地黄产量和质量比较[J]. 山东中医杂志, 2013(09):58-59+77. 5. 王素云, 卢颖, 蔡丹凤,等. 基于雌激素受体探讨梓醇对抗糖剥夺心肌细胞损伤的作用[J]. 中国药理学通报, 2019. 4. 和大奎, 朱文学, 于斌,等. 地黄浸膏超声真空干燥特性和动力学研究[J]. 江苏农业科学, 2017, 45(013):157-164. 3. 李民,辛杰,王春艳,李民,张淹.地黄中梓醇含量与产区相关性研究[J].中国药物评价,2014,31(04):212-214. 2. 张路 王春艳 李士栋 等. 响应面设计优化地黄中梓醇的提取工艺研究[J]. 中国药物评价 2015 000(001):12-16. 1. 周霞 张文倩 刘炬 李丽 刘付红 刘炳男.从血管内皮生长因子及其受体调控角度探讨地黄梓醇促血管新生作用及分子机制研究[J].实用心脑肺血管病杂志 2020 28(02):64-68.