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奥美拉唑

    
分析标准品,HPLC≥98%

Omeprazole

源叶
B24391 一键复制产品信息
73590-58-6
C17H19N3O3S
345.42
MFCD00083192
5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基亚砜]-1H-苯并咪唑;奥克;洛赛克
奥美拉唑(73590-58-6)
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
B24391-100mg
分析标准品,HPLC≥98%

¥150.00

2 3 1 - -

产品介绍

 Omeprazole (H 16868) 是一种质子泵 (proton pump) 抑制剂 (PPI),有潜力用于胃肠道疾病的研究。Omeprazole 竞争性抑制 CYP2C19 活性,Ki 为 2 到 6 μM。Omeprazole 还抑制革兰氏阳性菌和革兰氏阴性菌生长。Omeprazole 是中性鞘磷脂酶 (N-SMase) 的抑制剂(外泌体抑制剂)。

SMILES: O=S(C1=NC2=CC=C(OC)C=C2N1)CC3=NC=C(C)C(OC)=C3C
熔点: 156°C
沸点: 600°C at 760 mmHg
外观: white solid
溶解性: DMSO  :  ≥  100  mg/mL  (289.50  mM)

H2O  :  0.67  mg/mL  (1.94  mM;  Need  ultrasonic)
敏感性: 易吸潮;对光敏感
储存条件: 2-8℃
密度: 1.332
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(27篇)

22. [IF=8] Wang Xiaonan et al."Selective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide."Science China-Life Sciences.2025 Jan;:1-16 21. [IF=2.5] Ze Li et al."Sheng-Jiang-Yi-You decoction inhibits the inflammatory response by down-regulating the p38MAPK signaling pathway to alleviate Helicobacter pylori-associated gastritis."HISTOLOGY AND HISTOPATHOLOGY.2025 Mar 17:18906 20. [IF=4.8] Yang Deng et al."Risk assessment of CYP3A induction by ginsenosides’ metabolites from oral Panax notoginseng (Sanqi) extract."JOURNAL OF ETHNOPHARMACOLOGY.2025 Apr;:119864 19. [IF=4.9] Qing Qian et al."UHPLC method for simultaneous assessment of pharmacokinetic parameters of co-administered voriconazole and omeprazole using rat plasma."MICROCHEMICAL JOURNAL.2024 Dec;207:111729 18. [IF=3] Na Li et al."Chemical profiling and quality evaluation of raw and vinegar-processing frankincense by multiple UPLC-MS/MS techniques."PHYTOCHEMICAL ANALYSIS.2024 Aug;: 17. [IF=2.7] Guofang Bi et al."Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats."BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY.2024 Jun;: 16. [IF=3.3] Pinglong Fan et al."Dendrobium officinale flos water extract ameliorates ethanol-induced acute gastric mucosal injury via inhibiting oxidative stress and inflammation."JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE.2024 Jun;: 15. [IF=4.7] Sun Nan et al."Blockade of aryl hydrocarbon receptor restricts omeprazole-induced chronic kidney disease."JOURNAL OF MOLECULAR MEDICINE-JMM".2024 Mar;:1-14 14. [IF=2.9] Yuan Wang et al."Chemometrics-based Chemical Analysis of Myrrh and Its Vinegar-processed Products by UPLC-MS/MS."CHEMISTRY & BIODIVERSITY.2024 Jan;:e202301782 13. [IF=8.2] Na Li et al."A rapid-floating natural polysaccharide gel–raft with double-effect for the treatment of gastroesophageal reflux disease."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Mar;261:129667 12. [IF=3.9] Kunhui Sun et al."A Multichannel Fluorescent Array Sensor for Discrimination of Different Types of Drug-Induced Kidney Injury."SENSORS.2023 Jan;23(13):6114 11. [IF=6.911] Zhenwei Xiao et al."An effective pretreatment technique based on multi-walled carbon nanotubes to reduce the matrix effect in plasma samples analyzed by a new type probe electrospray ionization method."ANALYTICA CHIMICA ACTA.2023 Jul;1263:341268 10. [IF=5.364] Lisu Li et al."Bletilla striata Polysaccharide Nanoparticles Improved the Therapeutic Efficacy of Omeprazole on the Rat Gastric Ulcer Induced by Ethanol."MOLECULAR PHARMACEUTICS.2023;XXXX(XXX):XXX-XXX 9. [IF=5.719] Baoming Tian et al."Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats."Nutrients. 2022 Jan;14(7):1476 8. [IF=3.503] Yuzhu Zhang et al."Effects of psoralen on the pharmacokinetics of anastrozole in rats."Pharm Biol. 2018;56(1):433-439 7. [IF=3.659] Rong Qian et al."In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori."Bmc Complem Altern M. 2016 Dec;16(1):1-8 6. Rong, Qian, et al. "In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (SY Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori." BMC complementary and alternative medicine 1 5. Zhang, Yuzhu, et al. "Effects of psoralen on the pharmacokinetics of anastrozole in rats." Pharmaceutical biology 56.1 (2018): 433-439.https://doi.org/10.1080/13880209.2018.1501584 4. 魏文增,赵宁宁,林颖烽,王瑾,王宫.Cocktail探针法评价牛樟芝醇提物对人CYP450酶活性的影响[J].科技风,2021(03):139-140. 3. 陈瑞,周维,张丽,朱高峰,黄静,汤磊.树豆酮酸A对人肝微粒体中5种常见细胞色素P_(450)酶的体外抑制作用研究[J].中国药房,2021,32(02):195-200. 2. 魏文增,赵宁宁,林颖烽,王瑾,王宫.Cocktail探针法评价牛樟芝醇提物对人CYP450酶活性的影响[J].科技风,2021(03):139-140. 1. 景娴 江海 陈琛.UPLC-MS法同时检测大鼠血浆中6种CYP450探针药物浓度[J].陕西理工大学学报(自然科学版) 2018 34(01):59-65.

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