氧嗪酸钾

73. [IF=5.4] Hongxuan Yang, et al. "The mechanism of honeysuckle peptides in ameliorating hyperuricemia in mice via the PGC-1α/PPARγ/ABCG2 pathway"JOURNAL OF ETHNOPHARMACOLOGY, 2026 Feb;:121358 72. [IF=4.2] Wenqing Shi, et al. "Online 2D-LC-Q-TOF/MS and MALDI-MSI techniques were employed to elucidate the spatial distribution and metabolic regulation of the active components of Smilax glabra Roxb in the kidneys of hyperuricemia rats"Results in Chemistry, 2026 71. [IF=4.6] Danna Yan, et al. "Polyphenol-Rich Extract from Archidendron clypearia: Optimization, Characterization, and Hypouricemic Activity"MOLECULES, 2026 Apr;31(9):1451 70. [IF=9.7] Wenwen Ding, et al. "Green and efficient ultrasound-assisted supramolecular solvent extraction of Plantago asiatica L.: Process optimization, mechanism, and hypouricemic efficacy"ULTRASONICS SONOCHEMISTRY, 2026 Jun;129:107860 69. [IF=5.7] Ze Fu, et al. "Clematis Chinensis Attenuates Hyperuricemia Through the Coordinated Regulation of Purine Metabolism and Inflammatory Responses: An Integrative Study"Pharmaceuticals, 2026 May;19(6):830 68. [IF=5.1] Yanan Wang et al."Protective effects of polysaccharide SH-P-1-1 isolated from Phellinus igniarius on hyperuricemia and gout via intestinal microecosystem regulation."Frontiers in Nutrition.2025 Dec;12:1717561 67. [IF=5.1] Mingzhen Zhang et al."Bioactive Components, Untargeted Metabolomics and Bioinformatics of Chaenomeles speciosa Fruit on Uric Acid-Lowering Activity Assessment."Foods.2025 Dec;15(1):20 66. [IF=3.4] Ji-Wei Wang et al."Establishment of a novel cynomolgus monkey model of hyperuricemia."Animal Models and Experimental Medicine.2026 Jan;: 65. [IF=10.9] Mu-xuan Wang et al."Puerarin-loaded hyaluronic acid self-assembled nanoparticles ameliorate hyperuricemic nephropathy by modulating lipid peroxidation and macrophage polarization."Nano Today.2026 Feb;67:102983 64. [IF=5.1] Danping Zhao et al."Puerariae lobatae Radix aqueous extract ameliorates asymptomatic hyperuricemia in a potassium oxonate-induced rat model by dual modulation of uric acid production and excretion."Frontiers in Nutrition.2025 Nov;12:1685674 63. [IF=2.5] Jiang Xiaocui et al."Shenling Baizhu San attenuates testicular spermatogenic dysfunction in hyperuricemic mice via dual modulation of MAPK/NF-κB and NLRP3 inflammasome pathways."HEREDITAS.2025 Dec;162(1):1-18 62. [IF=4.9] Xiaoye An et al."Investigation of Pharmacological Mechanisms and Active Ingredients of Cichorium intybus L. in Alleviating Renal Urate Deposition via lncRNA H19/miR-21-3p Regulation to Enhance ABCG2 Expression."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 61. [IF=5.4] Kexin Li et al."Urate-lowering and renal-protective effects of sugarcane polyphenols in hyperuricemia: mechanisms and key components."Food & Function.2025 Aug;: 60. [IF=4.9] Xiaoye An et al."Investigation of Pharmacological Mechanisms and Active Ingredients of Cichorium intybus L. in Alleviating Renal Urate Deposition via lncRNA H19/miR-21-3p Regulation to Enhance ABCG2 Expression."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2 59. [IF=5.4] Kexin Li et al."Urate-lowering and renal-protective effects of sugarcane polyphenols in hyperuricemia: mechanisms and key components."Food & Function.2025 Aug;: 58. [IF=4.9] Ying Yang et al."Influence of Gut Microbiota-Derived Butyrate on Intestinal Uric Acid Excretion and Hyperuricemia Regulation by Cichorium intybus L.."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(13):6413 57. [IF=2.6] Ping Chen et al."Hederagenin’s uric acid-lowering effects in hyperuricemic mice: Mechanistic insights from molecular docking and in vivo analysis."PLoS One.2025 Jun;20(6):e0326317 56. [IF=4.9] Chengjin Lu et al."Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(11):5320 55. [IF=7.7] Zhenqiang Wang et al."Polysaccharide isolated from Dioscorea septemloba improves hyperuricemia and alleviates renal fibrosis through gut-kidney axis in mice."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Dec;282:137112 54. [IF=4.9] Songrui Di et al."Transcriptomic Analysis Reveals the Potential Mechanism of Cardamine circaeoides Hook.f. & Thomson in Lowering Serum Uric Acid by Reducing Inflammatory State Through CCR7 Target."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(23 53. [IF=4.9] Wanyun Dang et al."Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Dec;25(24):13399 52. [IF=4.8] Nuoshi Chen et al."Tinospora crispa (L.) Hook.f. & Thomson vines ameliorates hyperuricemia by inhibiting synthesis and promoting excretion of uric acid through targeting NLRP3/caspase-1/IL-1β pathway."JOURNAL OF ETHNOPHARMACOLOGY.2024 Dec;:119271 51. [IF=4] Xiaoyue Zhang et al."Bioactive Evaluation of Naringenin in Ameliorating Hyperuricemia-Induced Liver Injury by Inhibiting Xanthine Oxidase."eFood.2025 Jan;6(1):e70032 50. [IF=5.7] Tingting Zhang et al."Oleanolic Acid Alleviates Hyperuricemia via Gut Microbiota Control the Integrity of Gut Barrier and the Expressions of Urate Transporter in Mice."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;XXXX(XXX):XXX-XXX 49. [IF=2.5] Kang Ma et al."Chuanxiong Rhizoma extracts alleviate hyperuricaemia-induced renal injury by reducing serum UA levels and renoprotection."FITOTERAPIA.2025 Feb;:106456 48. [IF=4.7] Haoluan Wang et al."Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice."Foods.2025 Jan;14(7):1118 47. [IF=4] Jing Zhao et al."Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia."Frontiers in Microbiology.2025 Mar;16:1555734 46. [IF=4.4] Wenqing Shi et al."Comprehensive characterisation of the active ingredients of Smilax glabra Roxb based on chemical fingerprinting, metabolic fingerprinting and pharmacodynamic fingerprinting."Frontiers in Pharmacology.2025 Apr;16: 45. [IF=4.4] Nan Li et al."Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins."Frontiers in Pharmacology.2025 Apr;16: 44. [IF=4.4] Liu Mengwen et al."Evaluating renal injury characteristics in different rat models of hyperuricemia and elucidating pathological molecular mechanisms via serum metabolomics."Frontiers in Pharmacology.2024 Sep;15: 43. [IF=3.4] Yining Luo et al."Integrating network pharmacology and experimental models to investigate the mechanisms of XCHD and YCSLS in preventing HUA progression via TLR4/MYD88/NF-κB signaling."Heliyon.2024 Jul;10: 42. [IF=6.6] Ziwei Huang et al."Supersaturated Drug Delivery System of Oxyberberine Based on Cyclodextrin Nanoaggregates: Preparation, Characterization, and in vivo Application."International Journal of Nanomedicine. 41. [IF=5.2] Haiying Wang et al."Screening and evaluation of a novel nucleotide-degrading Levilactobacillus brevis grx821 with anti-hyperuricemia ability."Food Bioscience".2024 Aug;60:104337 40. [IF=5.4] Ying-Ling Zhang et al."Red ginseng ameliorates lipotoxicity-induced renal fibrosis in hyperuricemia mice."JOURNAL OF ETHNOPHARMACOLOGY".2024 Jun;327:118014 39. [IF=30.3] Ying-Xi Xu et al."Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia."Cell Host & Microbe.10.1016/j.chom.2024.02.001 38. [IF=4.6] Xinhe Wang et al."Analysis of Polyphenol Extract from Hazel Leaf and Ameliorative Efficacy and Mechanism against Hyperuricemia Zebrafish Model via Network Pharmacology and Molecular Docking."MOLECULES.2024 Jan;29(2):317 37. [IF=4.3] Guitao Xu et al."Eupatilin inhibits xanthine oxidase in vitro and attenuates hyperuricemia and renal injury in vivo."FOOD AND CHEMICAL TOXICOLOGY.2024 Jan;183:114307 36. [IF=6.1] Xiaofei Zhou et al."Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;XXXX(XXX):XXX-XXX 35. [IF=5.2] Weimin Hu et al."Identification of anti-hyperuricemic components from Cichorium intybus L. taproots."Food Bioscience.10.1016/j.fbio.2023.103145 34. [IF=5.2] Lin Xiang et al."Artemisia selengensis Turcz. leaves extract ameliorates hyperuricemia in mice by inhibiting hepatic xanthine oxidase activity, modulating renal uric acid transporters, and improving metabolic disorders."Food Bioscience.2023 Jun;:102639 33. [IF=5.2] Biqian Wei et al."Guluronate oligosaccharides exerts beneficial effects on hyperuricemia and regulation of gut microbiota in mice."Food Bioscience.2023 Jun;:102855 32. [IF=1.714] Ge Hongzhang et al."Dendrobium officinalis Six Nostrum Promotes Intestinal Urate Underexcretion via Regulations of Urate Transporter Proteins in Hyperuricemic Rats."COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING.2023 Apr;26(4):848-861 31. [IF=1.714] Qian Xvwu et al."The Anti-hyperuricemia and Anti-inflammatory Effects of Atractylodes Macrocephala in Hyperuricemia and Gouty Arthritis Rat Models."COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING.2023 Apr;26(5):950-964 30. [IF=4.319] Jing Huang et al."Wuling San Based on Network Pharmacology and in vivo Evidence Against Hyperuricemia via Improving Oxidative Stress and Inhibiting Inflammation."Drug Design Development and Therapy. 29. [IF=6.706] Biqian Wei et al."Ameliorative Effect of Mannuronate Oligosaccharides on Hyperuricemic Mice via Promoting Uric Acid Excretion and Modulating Gut Microbiota."Nutrients.2023 Jan;15(2):417 28. [IF=5.895] Xiaofei Zhou et al."Chlorogenic Acid Prevents Hyperuricemia Nephropathy via Regulating TMAO-Related Gut Microbes and Inhibiting the PI3K/AKT/mTOR Pathway."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2022;70(33):10182–10193 27. [IF=1.714] Wang Yu-Zhi et al."Effects of Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Fructose and Potassium Oxonate."COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING.2022 Jul;25(8):1294-1303 26. [IF=5.195] Yu Wang et al."An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery."JOURNAL OF ETHNOPHARMACOLOGY.2022 Sep;295:115450 25. [IF=6.706] Dan Wu et al."Tea (Camellia sinensis) Ameliorates Hyperuricemia via Uric Acid Metabolic Pathways and Gut Microbiota."Nutrients.2022 Jan;14(13):2666 24. [IF=6.543] Liu Lijun et al."Inflammatory Response and Oxidative Stress as Mechanism of Reducing Hyperuricemia of Gardenia jasminoides-Poria cocos with Network Pharmacology."Oxid Med Cell Longev. 2021;2021:8031319 23. [IF=2.629] Yao Rongmei et al."Tu-Teng-Cao Extract Alleviates Monosodium Urate-Induced Acute Gouty Arthritis in Rats by Inhibiting Uric Acid and Inflammation."Evid-Based Compl Alt. 2020;2020:3095624 22. [IF=2.629] Guo Lin-Feng et al."Effects and Mechanisms of Dendrobium officinalis Six Nostrum for Treatment of Hyperuricemia with Hyperlipidemia."Evid-Based Compl Alt. 2020;2020:2914019 21. [IF=3.981] Wenhao Xu et al."Self-assembled nanocapsules of celery (Apium graveolens Linn) seed oil: Mechanochemical preparation, characterization and urate-lowering activity."J Drug Deliv Sci Tec. 2021 Dec;66:102810 20. [IF=4.411] Xiaoke Wang et al."Novel Carbon Dots Derived from Puerariae lobatae Radix and Their Anti-Gout Effects."Molecules. 2019 Jan;24(22):4152 19. [IF=2.74] Yu Yun et al."Intestinal tract is an important organ for lowering serum uric acid in rats."Plos One. 2017 Dec;12(12):e0190194 18. Yun, Yu, et al. "Intestinal tract is an important organ for lowering serum uric acid in rats." PloS one 12.12 (2017): e0190194.https://doi.org/10.1371/journal.pone.0190194 17. Guo, Lin-Feng, et al. "Effects and mechanisms of Dendrobium officinalis six nostrum for treatment of Hyperuricemia with hyperlipidemia." Evidence-Based Complementary and Alternative Medicine 2020 (2020).https://doi.org/10.1155/2020/2914019 16. 徐梦琪,徐德平.土茯苓降尿酸活性成分研究[J].天然产物研究与开发,2020,32(11):1860-1865. 15. 黄柳绿,梅杰,潘立,王慧敏,李芳,张媛媛,寇俊萍,余伯阳.苏打水降尿酸作用的研究[J].现代食品,2020(22):164-169+173. 14. 康乐,苗晋鑫,苗明三,刘慧娟,李宁.芍药花总苷对小鼠高尿酸血症模型的药效机制研究[J].时珍国医国药,2020,31(08):1844-1846. 13. 石慧,梁晓珊,黄丽文,罗之纲,谭龙.电解饮用水促进高尿酸血症SD大鼠尿酸代谢[J].卫生研究,2020,49(05):802-808. 12. 邢志华, 包然, 姜婧雯,等. 芹菜素-钐配合物的合成及其抗小鼠高尿酸血症研究. 天然产物研究与开发. 11. 于俊俊, 徐德平. 枳椇子降尿酸功效成分[J]. 食品科技, 2019, v.44;No.337(11):234-238+244. 10. 吴杲, 吴汉斌, 蒋红. 虎杖苷的降尿酸作用及其机制研究[J]. 药学学报, 2014(12):1739-1742. 9. 张雅, 王一乔, 马卓雅,等. 药效学实验结合正交试验优选壮药柏金颗粒的水提醇沉工艺[J]. 中国药房, 2020, v.31;No.674(08):28-34. 8. 王露, 权利娜, 赵博,等. 牛蒡根总黄酮对高尿酸血症小鼠的影响[J]. 西北大学学报(自然科学版), 2019(5). 7. 王苗慧, 马鸿斌, 孙红旭,等. 清热排毒胶囊对高尿酸血症大鼠血尿酸及黄嘌呤氧化酶的影响[J]. 光明中医, 2014(05):950-952. 6. 石拓, 卢存龙, 李龙,等. 液相色谱-质谱研究高尿酸血症大鼠血清代谢组学[J]. 基础医学与临床, 2019, V39(03):337-342. 5. 李媛媛, 周海燕, 吴绿英,等. 大鼠高尿酸血症模型的建立与研究[J]. 中国实验动物学报, 2019, 027(006):747-752. 4. 刘静, 刘梅, 杨波,等. 地黄提取物对高尿酸血症小鼠的影响[J]. 中国药物应用与监测, 2015, v.12;No.70(06):347-350. 3. 杨雪芳 高克立 王永昌 et al. 加味四物四藤汤不同提取物对大鼠血尿酸及黄嘌呤氧化酶的影响[J]. 中国中医药信息杂志 2014 21(011):66-68. 2. 王泽 慈小燕 崔涛 魏滋鸿 张洪兵 刘睿 李亚卓 伊秀林 张铁军 谷元 武卫党 刘昌孝.不同药性成分对OAT4、URAT1抑制作用及对急性高尿酸血症小鼠血尿酸水平的影响[J].中草药 2019 50(05):1157-1163. 1. 卢存龙 李宇 李龙 等. Roux-en-Y胃旁路手术和袖状胃切除术对高尿酸血症大鼠代谢的影响及机制研究[J]. 中华肥胖与代谢病电子杂志 2017 3(4):198-207.