源叶
S17115
一键复制产品信息
62996-74-1
C28H26N4O3
466.53
MFCD00077402
链霉菌属十字孢碱;十字孢碱;星形孢菌素;StaurosporinefromStreptomycessp·
星孢菌素 USP级，98%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S17115-1mg |
USP级，98% | ￥200.00 |
>10 | 4 | 2 | - | - |
|
S17115-5mg |
USP级，98% | ￥650.00 |
>10 | - | - | - | - |
|
S17115-25mg |
USP级，98% | ￥1500.00 |
>10 | - | - | - | - |
|
产品介绍
Staurosporine 是一种有效，ATP 竞争性的，非选择性蛋白激酶抑制剂，抑制 PKC，PKA，c-Fgr，和 Phosphorylase kinase 的 IC50 分别为 6 nM，15 nM，2 nM，3 nM。Staurosporine 也抑制 TAOK2，IC50 值 3 μM。Staurosporine 是一个凋亡诱导剂。
| SMILES： | C[C@]12[C@@](OC)([H])[C@@](NC)([H])C[C@](O2)([H])N3C4=CC=CC=C4C5=C6C(CN=C6O)=C7C8=CC=CC=C8N1C7=C53 |
|---|---|
| 沸点： | 270℃ |
| 溶解性： | DMSO : 62.5 mg/mL (133.97 mM; Need ultrasonic) |
| 储存条件： | 2-8℃ |
| 密度： | 1·56 |
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(8篇)
8. [IF=2.6] Yuanyuan Liu, et al. "Si-Miao-Yong-An decoction restores macrophage efferocytosis and modulates vascular inflammation via PPAR-γ/MerTK pathway to treat atherosclerosis"FITOTERAPIA, 2026 Feb;:107118
7. [IF=4.9] Ziyi Zhong, et al. "Folate receptor-targeted cantharidin and staurosporine dual-drug nanoliposomes for multi-target synergistic therapy in hepatocellular carcinoma"JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2026 May;119:108176
6. [IF=6.5] Aiqiu Wei et al."Aptamer-Mediated Dual-Loaded Liposomal Nanosystem for Synergistic Therapy in Hepatocellular Carcinoma via mTOR/HIF-1α/VEGF Pathway."International Journal of Nanomedicine.2026 Jan;21:1-18
5. [IF=4.1] Yahui Ma et al."Lapachol, a naphthoquinone identified through chemical screening, inhibits plant immunity."PLANT SCIENCE.2025 Jul;:112659
4. [IF=14.3] Xietao Ye et al."Monocyte/Macrophage-Mediated Transport of Dual-Drug ZIF Nanoplatforms Synergized with Programmed Cell Death Protein-1 Inhibitor Against Microsatellite-Stable Colorectal Cancer."Advanced Science.2024 Aug;:2405886
3. [IF=3.6] Yuzhen Niu et al."Paeonol interferes with lupus nephritis by regulating M1/M2 polarization of macrophages."MOLECULAR IMMUNOLOGY".2024 May;169:66
2. [IF=11.467] Chao Li et al."Core-shell nanosystems designed for effective oral delivery of polypeptide drugs."JOURNAL OF CONTROLLED RELEASE.2022 Dec;352:540
1. [IF=6.023] Zhuang Hong et al."Rosmarinic acid attenuates acrylamide induced apoptosis of BRL-3A cells by inhibiting oxidative stress and endoplasmic reticulum stress."Food Chem Toxicol. 2021 May;151:112156
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