源叶
S17119
一键复制产品信息
11089-65-9
C39H64N4O16
844.94（n=10）
MFCD00065709
TunicamyClnfromStreptomyceslysosuperficus
衣霉素 高纯，98%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S17119-1mg |
高纯，98% | ￥350.00 |
>10 | >10 | 9 | - | - |
|
S17119-5mg |
高纯，98% | ￥1500.00 |
>10 | 2 | 2 | - | - |
|
S17119-25mg |
高纯，98% | ￥4000.00 |
>10 | - | - | - | - |
|
产品介绍
Tunicamycin 是一种同源核苷抗生素的混合物, 可抑制 N-糖基化并阻断 GlcNAc 磷酸转移酶 (GPT)。Tunicamycin 引起细胞内质网 (ER) 中未折叠蛋白的积累并诱导 ER 应激，并导致 DNA 合成受阻和 G1 期细胞周期停滞。Tunicamycin 可抑制革兰氏阳性细菌，酵母，真菌和病毒，并具有抗癌活性。Tunicamycin 增加宫颈癌细胞中外泌体的释放。
| SMILES： | CC(C)C/C=C/C(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CC(O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)O[C@@H]1O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4NC(C)=O |
|---|---|
| 熔点： | 234 - 235℃ |
| 外观： | 粉末 |
| 溶解性： | DMSO : 33.33 mg/mL (Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) |
| 储存条件： | 2-8℃,避光 |
| 用途： | 抗生素类药物、抗菌素、微生物代谢物、生化试剂 |
| 密度： | 1.57 |
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(11篇)
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10. [IF=4.1] Min-Jun Zhao et al."Integration of Network Pharmacology, Molecular Docking, and Experimental Validation to Identify the Effect of EGCG on Alleviating Chondrocyte Inflammatory Damage by Targeting ER Stress-STAT3 Crosstalk."Journal of Inflammation Research.
9. [IF=12.5] Yang Yang et al."Mitochondrial ROS trigger interorganellular signaling and prime ER processes to establish enhanced plant immunity."Science Advances.2025 Oct;11(40)
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7. [IF=4.8] Lu Liu et al."New insights into the antiadipogenic effect of dihydromyricetin by restoring lipid homeostasis between TG and PE in white adipose tissue."Food Bioscience.2025 Apr;66:106151
6. [IF=4.4] Haoxiang Sun et al."Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway."Frontiers in Pharmacology.2025 Apr;16:
5. [IF=15.8] Zhiyuan Hu et al."Nanoarchitectonics of in Situ Antibiotic-Releasing Acicular Nanozymes for Targeting and Inducing Cuproptosis-like Death to Eliminate Drug-Resistant Bacteria."ACS Nano.2024;XXXX(XXX):XXX-XXX
4. [IF=5.195] Yuling Liu et al."Jintiange proteins promote osteogenesis and inhibit apoptosis of osteoblasts by enhancing autophagy via PI3K/AKT and ER stress pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jul;311:116399
3. [IF=7.31] Qiao Lei et al."Biogenic Selenium Nanoparticles Alleviate Intestinal Epithelial Barrier Damage through Regulating Endoplasmic Reticulum Stress-Mediated Mitophagy."Oxidative Medicine and Cellular Longevity.2022;2022:3982613
2. [IF=7.31] Zhao Xu et al."Chrysophanol Ameliorates Hemin-Induced Oxidative Stress and Endoplasmic Reticulum Stress by Regulating MicroRNA-320-5p/Wnt3a Pathway in HT22 Cells."Oxidative Medicine and Cellular Longevity.2022;2022:9399658
1. [IF=4.044] Yang Yong et al."Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia."Cell Tissue Res. 2020 Mar;379(3):589-599
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