尼日利亚菌素 ≥97%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S25116-5mg |
≥97% | ￥400.00 |
>10 | 3 | 1 | - | - |
|
S25116-25mg |
≥97% | ￥1610.00 |
>10 | - | - | - | - |
|
S25116-100mg |
≥97% | ￥3540.00 |
>10 | - | - | - | - |
|
产品介绍
Nigericin 是一种源自吸水链霉菌的抗生素，可以充当一种离子载体 (K+/H+ ionophore)，促进跨线粒体膜的 K+/H+ 交换。Nigericin 可以 NALP3 依赖性方式诱导 IL-1β 释放，可作为 NLRP3 活化剂。Nigericin 触发红细胞衰亡，与 ROS 的形成同时发生，部分是由于氧化应激的诱导。Nigericin 引发细胞凋亡 (apoptosis)。
| SMILES： | C[C@H]1[C@]2(O[C@@](C)(C1)[C@@]3(O[C@@](C)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H])O[C@H](C[C@@H]6O[C@@]([C@H](C(O)=O)C)([C@@H](C)CC6)[H])C[C@@H](OC)[C@H]2C |
|---|---|
| 熔点： | 245-255℃ |
| 沸点： | 779.9℃ at 760mmHg |
| 外观： | 白色固体 |
| 溶解性： | ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| 储存条件： | 2-8℃ |
| 密度： | 1.19 |
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(15篇)
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11. [IF=2.6] Xiaofei Yin et al."A colorimetric and turn-on fluorescent probe for visualization of lysosomal pH fluctuation."Analytical Methods.2025 Aug;:
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9. [IF=14.1] Jian Cui et al."Inhibition of RACK1-Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome."Advanced Science.2025 May;:2411355
8. [IF=9] ZhangTingting et al."Targeting HPK1 inhibits neutrophil responses to mitigate post-stroke lung and cerebral injuries."EMBO Molecular Medicine.
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5. [IF=9.4] Guangning Wang et al."Resting cell formation in the marine diatom Thalassiosira pseudonana."NEW PHYTOLOGIST".2024 Feb;:
4. [IF=3] Zhixuan Sun et al."Development of multiplex immunochromatographic assay for the simultaneous detection of three polyether ionophore antibiotics in chicken muscle."FOOD AND AGRICULTURAL IMMUNOLOGY.2023;34(1):Article: 2260124
3. [IF=2.264] Yu Zhang et al."Blocking CXC Motif Chemokine Ligand 2 Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Apoptosis and NLRP3 Inflammasome Activation."BIOLOGICAL & PHARMACEUTICAL BULLETIN.2023 May;46(5):672-683
2. [IF=6.208] Xianwen Ye et al."Structural-Activity Relationship of Rare Ginsenosides from Red Ginseng in the Treatment of Alzheimer’s Disease."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(10):8625
1. [IF=7.109] Hou Yapeng et al."Expression profiles of respiratory V-ATPase and calprotectin in SARS-CoV-2 infection."Cell Death Discovery.2022 Aug;8(1):1-7
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