神经氨酸酶(微生物) ≥25u/mg solid
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S31133-100u |
≥25u/mg solid | ￥400.00 |
8 | 3 | 2 | - | 2 |
|
S31133-250u |
≥25u/mg solid | ￥800.00 |
9 | 6 | 4 | - | 4 |
|
S31133-1ku |
≥25u/mg solid | ￥2080.00 |
5 | 1 | 2 | - | - |
|
产品介绍
神经氨酸酶是一种水解酶，其可促进流感病毒从感染细胞释放并促进病毒的传播。
活力定义：one unit causes the hydrolysis of micromole of sialyllactos(oxidation of one micromole of NADH)per minute at PH 6.5 at 37℃
Molecular weight ：52 kDa (SDS-PAGE)
Isoelectric point 5.86
Michaelis constant: 1.02mM(sialyllactose pH6.5)
Optimum pH: 5.0
Optimum temperature: 50℃（酶活最高，不是最稳定的温度，稳定温度建议40℃以下）
pH Stability ：4.0~10.0 (25℃, 25hr)
Thermal stability ：< 40℃ (pH 7.5, 10min)
Enzyme Commission Number: EC 3.2.1.18 神经氨酸酶也称唾液酸酶（EC 3.2.1.18）。神经氨酸酶负责催化唾液酸与糖蛋白之间糖苷键的水解形成游离的N-乙酰神经氨酸，而游离的 N-乙酰神经氨酸在N-乙酰神经氨酸醛缩酶的作用下裂解产生丙酮酸。此酶可与N-乙酰神经氨酸醛缩酶、乳酸脱氢酶、丙酮酸氧化酶一起检测唾液酸的含量。
| 外观： | 白色粉末 |
|---|---|
| 溶解性： | 推荐稀释缓冲液：pH6.5 0.1M PIPES 含0.125%BSA |
| 敏感性： | 易潮湿 |
| 储存条件： | -20℃ |
| EC编号： | 3.2.1.18 |
| 用途： | A hydrolytic enzyme that removes sialic acid from mucoproteins |
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(10篇)
10. [IF=8] Zhenqing Zhang et al."Shield and bridge: Dual functions of glycan chains in ovomucin structure stability and gel network formation."FOOD RESEARCH INTERNATIONAL.2026 Mar;227:118289
9. [IF=6.1] Menghan Chen et al."Competitive Ultrafiltration: A Ligand-Displacement Strategy for Rapid Discovery of High-Quality Neuraminidase Inhibitors from Natural Product Mixtures."TALANTA.2025 Oct;:128948
8. [IF=10.7] Xueqi Su et al."Glycan-Anchored Fluorescence Labeling of Milk-Derived Extracellular Vesicles for Investigating Their Cellular Uptake and Intracellular Fate."Small Methods.2025 Feb;:2401996
7. [IF=10] Bo He et al."An Endocellulase-triggered NO Targeted-Release Enzyme-Prodrug Therapy System and Its Application in Ischemia Injury."Advanced Healthcare Materials.2024 Jun;:2401599
6. [IF=18.5] Kaiming Li et al."A Dual Enhancing Strategy of Novel Nanovaccine Based on TIM3 Silencing Nanoadjuvants and Desialylated Cancer Cell Membrane Antigens for Personalized Vaccination Immunotherapy of Cancer."ADVANCED FUNCTIONAL MATERIALS.2024 Jun;:2404956
5. [IF=3] Xiaofan Fan et al."Screening and identification of neuraminidase inhibitors from Baphicacanthus cusia by a combination of affinity ultrafiltration, HPLC-MS/MS, molecular docking, and fluorescent techniques."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGI
4. [IF=5.6] Xu Wencheng et al."Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-κB signaling pathway."Frontiers in Pharmacology.2023 Jun;14:
3. [IF=7.666] Chunyan Yang et al."Desialylated Mesenchymal Stem Cells-Derived Extracellular Vesicles Loaded with Doxorubicin for Targeted Inhibition of Hepatocellular Carcinoma."Cells.2022 Jan;11(17):2642
2. [IF=4.759] Yichao Zang et al."Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds."J
1. Zang, Yichao, et al. "Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds.
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