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乙酰胆碱酯酶(电鳗鱼)

    
200-1000 u/mg protein

ACHE;Acetylcholinesterase;Acetylcholine acetylhydrolase;Cholinesterase, Acetyl

源叶
S31315 一键复制产品信息
9000-81-1
MFCD00081268
货号 规格 价格 上海 北京 武汉 南京 购买数量
S31315-500u赠底物
200-1000 u/mg protein ¥1400.00 >10 - - -
S31315-2ku赠底物
200-1000 u/mg protein ¥4000.00 >10 - - -
S31315-10ku赠底物
200-1000 u/mg protein ¥13000.00 8 - - -
产品介绍 参考文献(59篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

酶活定义:One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37 °C.

类型:Type VI-S

性状:含 Tris 缓冲盐的冻干粉

分子量: 280 kDa

等电点: 5.5

外观: 类白色或褐色粉末
溶解性: 20  mM  Tris  HCl  buffer,  pH  7.5:  soluble1.0  mg/mL,  clear(lit.)
储存条件: -20℃
用途: Major degradative enzyme for acetylcholine in vivo. Converts acetylcholine + H2O to choline + acetic acid.
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(59篇)

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[IF=3.5] Yangzom Dawa et al."Screening and Characterization of Potential Acetylcholinesterase Inhibitors From Phyllanthus emblica L. Fruits Using Affinity Ultrafiltration Combined With Ultra-High-Performance Liquid Chromatography–Mass Spectrometry."JOURNAL OF FOOD 49. [IF=3.2] Xuhui Zhang et al."An Electrochemiluminescence Biosensor for Detection of Methyl Parathion With a Novel Probe Ru-MIL-100 via the Acetylcholinesterase Inhibition Coupled With the Reaction Between HAc and Triethylamine."LUMINESCENCE.2025 Jan;40(1):e70073 48. [IF=3.1] Yangzom Dawa et al."Cellulose filter paper immobilized acetylcholinesterase for rapid screening of enzyme inhibitors in Phyllanthus emblica L.."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2025 Jan;:116669 47. [IF=5.7] Jia-Nuo Zhang et al."Integration of High-Resolution LC-Q-TOF Mass Spectrometry and Multidimensional Chemical−Biological Analysis to Detect Nanomolar-Level Acetylcholinesterase Inhibitors from Different Parts of Zanthoxylum nitidum."JOURNAL OF AGRICULTURAL 46. [IF=4.7] Fan Minxia et al."Antiparasitic Activity and Potential Active Compounds from Azadirachta Indica Revealed by Affinity Ultrafiltration Chromatography–Mass Spectrometry with Acetylcholinesterase and Lactate Dehydrogenases."Journal of Analysis and Testing".20 45. [IF=6.1] Chen-Hui Chen et al."Novel Flavonol Alkaloids in Green Tea: Synthesis, Detection, and Anti-Alzheimer’s Disease Effect in a Transgenic Caenorhabditis elegans CL4176 Model."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY".2024;XXXX(XXX):XXX-XXX 44. 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[IF=4.952] Bailiang Zheng et al.Green extraction of phenolic compounds from foxtail millet bran by ultrasonic-assisted deep eutectic solvent extraction: Optimization, comparison and bioactivities.Lwt Food Sci Technol. 2022 Jan;154:112740 35. [IF=2.861] Hui-Na Yao et al."Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers."Natural Product Research. 2019 Dec 07 34. [IF=3.205] Hua Guo et al."A strategy to discover selective α-glucosidase/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening."J Chromatogr B. 2021 Jun;1174:122722 33. [IF=3.205] Hui-Peng Song et al."A strategy to discover lead chemome from traditional Chinese medicines based on natural chromatogram-effect correlation (NCEC) and natural structure-effect correlation (NSEC): Mahonia bealei and Mahonia fortunei as a case study."J Chr 32. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 31. [IF=4.24] Nana Li et al."Characterization of phenolic compounds and anti-acetylcholinase activity of coconut shells."Food Biosci. 2021 Aug;42:101204 30. [IF=4.616] Jiarui Yu et al."A photoelectrochemical sensor based on an acetylcholinesterase-CdS/ZnO-modified extended-gate field-effect transistor for glyphosate detection."Analyst. 2021 Jul;146(14):4595-4604 29. [IF=5.833] Qing Zhihe et al."Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides."Microchim Acta. 2020 Sep;187(9):1-9 28. [IF=6.986] Yue Hu et al."Dual-Mode Sensing Platform for Electrochemiluminescence and Colorimetry Detection Based on a Closed Bipolar Electrode."Anal Chem. 2021;93(36):12367–12373 27. [IF=7.46] Shaoqing Lu et al."Highly sensitive and label-free detection of catalase by a H2O2-responsive liquid crystal sensing platform."Sensor Actuat B-Chem. 2021 Oct;344:130279 26. [IF=10.588] Qipeng Shi et al."In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants."J Hazard Mater. 2021 May;409:124999 25. [IF=4.142] Wang Xiaoyan et al."A novel switchable fluorescent sensor for facile and highly sensitive detection of alkaline phosphatase activity in a water environment with gold/silver nanoclusters."Anal Bioanal Chem. 2019 Feb;411(5):1009-1017 24. [IF=5.833] Zhang Fangmei et al."Enzymatic determination of uric acid using water-soluble CuInS/ZnS quantum dots as a fluorescent probe."Microchim Acta. 2018 Nov;185(11):1-8 23. [IF=6.543] Zhang Jing et al."Studies of the Anti-amnesic Effects and Mechanisms of Single and Combined Use of Donepezil and Ginkgo Ketoester Tablet on Scopolamine-Induced Memory Impairment in Mice."Oxid Med Cell Longev. 2019;2019:8636835 22. [IF=6.986] Yue Zhao et al."Detection of Various Biomarkers and Enzymes via a Nanocluster-Based Fluorescence Turn-on Sensing Platform."Anal Chem. 2018;90(24):14578–14585 21. [IF=7.1] Fangmei Zhang et al."Dopamine-modified Mn-doped ZnS quantum dots fluorescence probe for the sensitive detection of tyrosinase in serum samples and living cells imaging."Sensor Actuat B-Chem. 2018 Mar;256:1069 20. Longbin Xu, Xu He, Pinyi Ma, Xin Liu, Fangmei Zhang, Ying Sun, Daqian Song, Xinghua Wang, A water-soluble fluorescent probe for the sensitive detection of endogenous alkaline phosphatase in living cells, Dyes and Pigments, Volume 159, 2018, Pages 584-589, 19. Zhang, Fangmei, et al. "Dopamine-modified Mn-doped ZnS quantum dots fluorescence probe for the sensitive detection of tyrosinase in serum samples and living cells imaging." Sensors and Actuators B: Chemical 256 (2018): 1069-1077.https://doi.org/10.1016/j.s 18. Wang, X., Liu, Z., Zhao, W. et al. A novel switchable fluorescent sensor for facile and highly sensitive detection of alkaline phosphatase activity in a water environment with gold/silver nanoclusters. Anal Bioanal Chem 411, 1009–1017 (2019). https://doi.o 17. Qing, Z., Li, Y., Li, Y. et al. Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides. Microchim Acta 187, 497 (2020). https://doi.org/10.1007/s00604-020-04486-2 16. Zhai, Meng‐Yu, et al. "Development of a novel nano‐based detection card by electrospinning for rapid and sensitive analysis of pesticide residues." Journal of the Science of Food and Agriculture 100.12 (2020): 4400-4408.https://doi.org/10.1002/jsfa.10477 15. 王焕南, 杨华, 顾英琳,等. 牡蛎共生细菌的分离,鉴定及次级代谢产物生物活性研究[J]. 聊城大学学报(自然科学版), 2019(5). 14. 王焕南, 赵艳, 王向月,等. 日照海域牡蛎共生真菌的分离,鉴定及生物活性研究[J]. 济宁医学院学报, 2020(3):188-193. 13. 凌庆枝, 董丽辉, 范三微,等. 蛇足石杉体内抑制乙酰胆碱酯酶活性物质的内生真菌的分离[J]. 安徽农业科学, 2012(30):14706-14707. 12. 罗琴, 祖云鸿, 石开琼,等. 微酸性电解水去除蔬菜农药残留效果的研究[J]. 食品安全质量检测学报, 2014(11):3657-3663. 11. 韩岚 季兆洁 陈卫东 等. 四物汤对血管性痴呆大鼠的神经保护作用及其机制研究[J]. 安徽中医药大学学报 2015 34(4):69-73. 10. 邢志恒, 吕娜, 何忠梅,等. 黄藤素衍生物的合成及其抑制乙酰胆碱酯酶活性研究[J]. 分析化学, 2018, 46(005):684-689. 9. 何忠梅,吕娜,南敏伦,赵昱玮,赫玉芳,孟令文,孙佳明,张连学.靶向亲和-液相色谱-质谱联用技术快速筛选黄藤总生物碱中乙酰胆碱酯酶抑制剂[J].分析化学,2017,45(02):211-216. 8. 常艳兵,杨晓丽,何琼.铂钴合金修饰的乙酰胆碱酯酶生物传感器的研制铂钴合金修饰的乙酰胆碱酯酶生物传感器的研制[J].云南化工,2013,40(04):1-5. 7. 郭明,燕冰宇,周珊,王春鹏,储富祥.纤维素基固载酶材料的制备及乙酰胆碱酯酶的固定化性能[J].高分子材料科学与工程,2013,29(10):150-154+159. 6. 伍周玲, 燕冰宇, 梁东军,等. 新型固载酶生物传感器制备及食品中有机磷农药检测[J]. 中国食品学报, 2015, 15(003):166-174. 5. 伍周玲, 梁东军, 郭明,等. 新型固定化乙酰胆碱酯酶传感器的制备及氨基甲酸酯农残检测[J]. 浙江农林大学学报, 2014(3). 4. 郭明 梁东军 谭贤. 农药残留检测用新型碳纳米管固载酶生物传感器的制备及其电学传感性能分析[J]. 农药学学报 2014. 3. 于浩然 高翔 田振坤 等. 五味子各萃取物抗氧化作用及抑制乙酰胆碱酯酶活性研究[J]. 现代中药研究与实践 2017 031(004):33-36. 2. 巫川 王树涛 朱婧 尤宏.BDE-47和BDE-209对乙酰胆碱酯酶(AChE)活性的抑制特性及分子作用力研究[J].生态毒理学报 2017 12(06):99-106. 1. 曹婷婷 陈俊涛 杨春柳 田云锋 冯腾垒 马正月.4-吡啶基噻唑-2-胺衍生物的设计、合成及其对乙酰胆碱酯酶的抑制活性研究[J].药学学报 2016 51(09):1436-1440.

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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