![6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶（866405-64-3）](images/tansoole/866405-64-3.gif)
6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶 ≥98%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S31490-5mg促销 |
≥98% | ￥245.00 ￥98.00 |
>10 | - | - | - | - |
|
S31490-25mg促销 |
≥98% | ￥740.00 ￥212.00 |
>10 | - | - | - | - |
|
S31490-100mg促销 |
≥98% | ￥2000.00 ￥440.00 |
10 | - | - | - | - |
|
产品介绍
Dorsomorphin (Compound C) 是一种选择性，ATP 竞争性的 AMPK 抑制剂 (在没有 AMP 的情况下，Ki 为 109 nM)。Dorsomorphin 选择性抑制 BMP I 型受体 ALK2，ALK3 和 ALK6。Dorsomorphin 诱导自噬 (autophagy) 作用。
| SMILES： | C(CN1CCCCC1)OC1=CC=C(C=C1)C1=CN2N=CC(=C2N=C1)C1=CC=NC=C1 |
|---|---|
| 溶解性： | 1M HCl : 50 mg/mL (125.16 mM; ultrasonic and adjust pH to 1 with HCl) DMSO : 5 mg/mL (12.52 mM; ultrasonic and warming and heat to 80°C) Ethanol : 3.33 mg/mL (8.34 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) |
| 储存条件： | 2-8℃ |
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(5篇)
5. [IF=2] Zewei Cong et al."Astragalus polysaccharide protects against neuron degeneration and mitochondrial dysfunction in Parkinson's disease by upregulating CEND1."HISTOLOGY AND HISTOPATHOLOGY.2026 Jan 15:25033
4. [IF=2.2] Wang Sen et al."The effect of Miya on skeletal muscle changes by regulating gut microbiota in rats with osteoarthritis through AMPK pathway."BMC MUSCULOSKELETAL DISORDERS.2024 Dec;25(1):1-11
3. [IF=2.9] Liu Yong-Qi et al."UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells."JOURNAL OF MOLECULAR HISTOLOGY.2025 Feb;56(1):1-13
2. [IF=6.1] Xing Cong et al."Metformin enhances endogenous neural stem cells proliferation, neuronal differentiation, and inhibits ferroptosis through activating AMPK pathway after spinal cord injury."Journal of Translational Medicine.2024 Dec;22(1):1-19
1. [IF=4.631] Dan-Dan Wang et al."AMPK/SIRT1 Deficiency Drives Adjuvant-Induced Arthritis in Rats by Promoting Glycolysis-Mediated Monocytes Inflammatory Polarization."Journal of Inflammation Research.2022; 15: 4663–4675
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