产品描述: | IRBP (1-20), human 包含 H-2b 单倍型的主要表位。IRBP (1-20), human TFA 诱导 H-2b 小鼠实验性自身免疫性葡萄膜视网膜炎 (EAU)。 |
体内研究: |
IRBP (1-20), human TFA induces EAU. For determination of proliferative and cytokine responses, lymph node and spleen cells are collected 21 days after immunization and are stimulated in culture with the appropriate antigen. Cells of C57BL/6 mice and 129/J mice immunized with IRBP (1-20), human TFA proliferated in response to the peptide. |
参考文献: |
1. Avichezer D, et al. Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice. Exp Eye Res. 2000;71(2):111‐118. [Content Brief]
2. Avichezer D, Silver PB, Chan CC, Wiggert B, Caspi RR. Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype. Invest Ophthalmol Vis Sci. 2000;41(1):127‐131. |
溶解性: |
soluble in DMSO |
保存条件: |
-20℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
0.456 ml |
2.278 ml |
4.557 ml |
5 mM |
0.091 ml |
0.456 ml |
0.911 ml |
10 mM |
0.046 ml |
0.228 ml |
0.456 ml |
50 mM |
0.009 ml |
0.046 ml |
0.091 ml |
|
注意: |
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