| 产品描述: | 钠通道抑制剂;Sodium Channel Inhibitors;;InformationLevobupivacaine Levobupivacaine (Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine), the S (-)-enantiomer of bupivacaine, is a long-acting amide local anaesthetic used in analgesia and anaesthesia. Levobupivacaine exhibits effects on motor and sensory nerves by inhibiting the opening of voltage-gated sodium channels .Targetsvoltage-gated sodium channels |
| 靶点: |
Sodium channels, Ferroptosis |
| 体内研究: |
Levobupivacaine (40 μmol/kg; IP; once daily for 25 days) significantly inhibits SGC7901 cell growth, and enhances the lipid ROS accumulation. Levobupivacaine (5 or 36 mg/kg; IP; single dosage) increases the latency to partial seizures and prevents the occurrence of generalized seizures at low dosage; reduces the latency to N-methyl-d-aspartate (NMDA)-induced seizures and increased seizure severity at high dosage. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.467 ml |
17.335 ml |
34.67 ml |
| 5 mM |
0.693 ml |
3.467 ml |
6.934 ml |
| 10 mM |
0.347 ml |
1.734 ml |
3.467 ml |
| 50 mM |
0.069 ml |
0.347 ml |
0.693 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |