货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
S55604-1ml促销	10mM in DMSO	￥206.00 ￥185.00 S55604-1ml ￥185.00 现货	5 5	-	-	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

S55604-1ml促销

10mM in DMSO

￥206.00 ￥185.00

产品描述：

L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.;L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.An irreversible inhibitor of 3-ketodihydrosphingosine synthetase

体内研究：

L-Cycloserine (25-50 mg/kg，腹腔注射，单次剂量) 在小鼠中有抗惊厥效果。
L-Cycloserine (30-100 mg/kg，口服或腹腔注射，一日两次，5 天) 增强对小鼠 GABA-T 活性的抑制作用，并提高抗癫痫作用。
L-Cycloserine (100-150 mg/kg，皮下注射或腹腔注射，每日一次，1 周) 通过皮下注射可使小鼠脑内脑苷含量降低 28%，对神经节苷含量无影响，腹腔注射导致神经节苷脂和脑苷和硫脂水平降低。
L-Cycloserine (100 mg/kg，皮下注射或腹腔注射，单次剂量) 注射方式对 3-酮二氢鞘氨醇合成酶抑制程度有影响。

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	9.795 ml	48.976 ml	97.953 ml
5 mM	1.959 ml	9.795 ml	19.591 ml
10 mM	0.98 ml	4.898 ml	9.795 ml
50 mM	0.196 ml	0.98 ml	1.959 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

L-环丝氨酸

L-Cycloserine

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)