| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S57071-1ml促销 |
10mM in DMSO | ￥692.00 ￥622.00 |
7 | - | - | - | - |
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| 产品描述： | 选择性PTEN抑制剂;Selective PTEN inhibitor;产品介绍SF1670 是一种有效的特异性的人第10号染色体缺失的磷酸酶及张力蛋白同源蛋白 (PTEN) 抑制剂。;Product introductionSF1670 is a potent and specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitorApplicationSF1670 has been used:• To study the effect of microRNA-30a on PTEN (phosphatase and tensin homologue deleted on chromosome 10 ) expression regulation.• To study the formation of autophagosomes, induced by EGF (Epidermal growth factor) - dependent PTEN expression.• To study the role of PTEN in the regulation of autophagy induction in human normal endometrial stromal cells. | ||||||||||||||||||||
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| 靶点： | PTEN | ||||||||||||||||||||
| 体内研究： | SF1670（3 mg/kg；i.p.）在小鼠中通过闭塞双侧颈动脉诱发全脑缺血 (17 min) 和再灌注 (24 min) 损伤后触发后处理。 | ||||||||||||||||||||
| 参考文献： | 1. Li Y, et al. Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. Blood. 2011 Jun 16;117(24):6702-13. 2. Montales MT, et al. Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells. Genes Nutr. 2015 Nov;10(6):49. 3. Amarjot Kaur Grewal, et al. Neuroprotective effect of pharmacological postconditioning on cerebral ischaemia-reperfusion-induced injury in mice. J Pharm Pharmacol. 2019 Jun;71(6):956-970. |
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| 保存条件： | -80℃（运输条件：冰袋低温运输） | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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