| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
| S80185-5mg | 99% | ￥160.00 | 9 | - | - | - |
|
| S80185-10mg | 99% | ￥304.00 | 10 | - | - | - |
|
| S80185-25mg | 99% | ￥576.00 | 7 | - | - | - |
|
| S80185-50mg | 99% | ￥1032.00 | 4 | - | - | - |
|
(-)-Dizocilpine maleate ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-Dizocilpine maleate is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM. (-)-Dizocilpine maleate has antidepressant effects
| 产品描述： | (-)-Dizocilpine maleate ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-Dizocilpine maleate is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM. (-)-Dizocilpine maleate has antidepressant effects | ||||||||||||||||||||
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| 靶点： | Ki: 211.7 nM (N-methyl-D-aspartate (NMDA) receptor);NMDAR;iGluR | ||||||||||||||||||||
| 体内研究： | (-)-Dizocilpine maleate (0.1 mg/kg; intraperitoneal injection; male adult C57BL/6 mice) treatment induces rapid antidepressant effects in the social defeat stress model | ||||||||||||||||||||
| 参考文献： | 1. Yang B, et al. Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model. Int J Neuropsychopharmacol. 2016 Dec 30;19(12). 2. Nishimura M, et al. MK-801 blocks monoamine transporters expressed in HEK cells. FEBS Lett. 1998 Feb 27;423(3):376-80. | ||||||||||||||||||||
| 溶解性： | DMSO : 100 mg/mL (296.41 mM; Need ultrasonic) Ethanol : 25 mg/mL (74.10 mM; Need ultrasonic) H2O : 8.33 mg/mL (24.69 mM; ultrasonic and warming and heat to 60°C) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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