| 产品描述： | Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies. |
| 靶点： |
DNA Alkylation;DNA Alkylator/Crosslinker;DNAAlkylator/Crosslinker;DNAAlkylation |
| 细胞实验： |
CDDP-resistant (KB-R) cells and parental cells (KB) pair were used. Viability was assessed using the MTT and clonogenic assay. Real-time polymerase chain reaction (PCR), glutathione (GSH) assay, and flow cytometric analysis were used for further assessment |
| 参考文献： |
1. Yamano Y , Shiiba M , Negoro K , et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells[J]. Head & Neck, 2010, 33(3):309-317. 2. Bhargava A , Vaishampayan U N . Satraplatin: leading the new generation of oral platinum agents[J]. Expert Opinion on Investigational Drugs, 2009, 18(11):1787-1797. |
| 溶解性： |
Soluble in DMSO |
| 保存条件： |
-20°C |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.999 ml |
9.994 ml |
19.989 ml |
| 5 mM |
0.4 ml |
1.999 ml |
3.998 ml |
| 10 mM |
0.2 ml |
0.999 ml |
1.999 ml |
| 50 mM |
0.04 ml |
0.2 ml |
0.4 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京