源叶(MedMol)
S80363
一键复制产品信息
144875-48-9
C17H22N4O2
314.382
雷西莫特;4-氨基-2-乙氧基甲基-ALPHA,ALPHA-二甲基-1H-咪唑并[4,5-C]喹啉-1-乙醇;1-(4-氨基-2-(乙氧基甲基)-1H-咪唑并[4,5-C]喹啉-1-基)-2-甲基-2-丙醇;RESIQUIMOD;1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-C]quinolin-1-yl]-2-methylpropan-2-ol;Chebi
RESIQUIMOD 99.80%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80363-5mg买3赠1 |
99.80% | ￥95.00 |
4 | - | - | - | - |
|
S80363-10mg促销 |
99.80% | ￥136.00 ￥110.00 |
4 | - | - | - | - |
|
S80363-25mg买3赠1 |
99.80% | ￥170.00 |
4 | - | - | - | - |
|
S80363-100mg买3赠1 |
99.80% | ￥476.00 |
8 | - | - | - | - |
|
S80363-200mg买3赠1 |
99.80% | ￥700.00 |
2 | 1 | - | - | - |
|
S80363-500mg |
99.80% | ￥1220.00 |
1 | - | - | - | - |
|
S80363-1g |
99.80% | ￥2150.00 |
1 | - | - | - | - |
|
| 产品描述： | Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | TLR7;TLR8;HCVProtease;TLR | ||||||||||||||||||||
| 体内研究： | Resiquimod (R-848) (50 μg/bird, i.m. route) significantly up-regulates the expression of IFN-α, IFN-β, IFN-γ, IL-1β, IL-4, iNOS and MHC-II genes in SPF chicken | ||||||||||||||||||||
| 参考文献： | 1. Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32. 2. Brugnolo F, et al. The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells. J Allergy Clin Immunol. 2003 Feb;111(2):380-8. 3. Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20. | ||||||||||||||||||||
| 溶解性： | DMF : 50 mg/mL (159.04 mM; Need ultrasonic) DMSO : ≥ 30 mg/mL (95.43 mM) Methanol : 25 mg/mL (79.52 mM; Need ultrasonic) H2O : 0.1 mg/mL (0.32 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(2篇)
2. [IF=3] Huimin Wu, et al. "Prunetin ameliorates myocardial pyroptosis after myocardial infarction by inhibiting the TNF-α/p38 MAPK/ERK pathway"Frontiers in Cardiovascular Medicine, 2026 Jul;13:1847407
1. [IF=10] Yao Jiang et al."Macrophage-Derived Nanosponges Adsorb Cytokines and Modulate Macrophage Polarization for Renal Cell Carcinoma Immunotherapy."Advanced Healthcare Materials".2024 Apr;:2400303
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