| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80579-2mg买3赠1 |
≥99% | ￥170.00 |
货期：2-3天 | - | - | - | - |
|
S80579-5mg买3赠1 |
99.70% | ￥270.00 |
8 | - | - | - | - |
|
S80579-10mg买3赠1 |
99.70% | ￥400.00 |
2 | - | - | - | - |
|
S80579-25mg买3赠1 |
99.70% | ￥640.00 |
5 | - | - | - | - |
|
S80579-50mg买3赠1 |
≥99% | ￥1120.00 |
货期：2-3天 | - | - | - | - |
|
S80579-100mg买3赠1 |
≥99% | ￥1680.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | hGSK-3α:77.5 nM (IC50);hGSK-3β:77.5 nM (IC50);Apoptosis;GSK-3 | ||||||||||||||||||||
| 参考文献： | 1. Coghlan MP, et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem Biol. 2000 Oct;7(10):793-803. 2. Pizarro JG, et al. Neuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons. Int J Dev Neurosci. 2008 May-Jun;26(3-4):269-76. 3. MacAulay K, et al. Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase. Eur J Biochem. 2003 Sep;270(18):3829-38. | ||||||||||||||||||||
| 溶解性： | DMSO : 100 mg/mL (277.99 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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