| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80623-2mg买3赠1 |
99.70% | ￥80.00 |
4 | - | - | - | - |
|
S80623-5mg买3赠1 |
99.70% | ￥100.00 |
6 | - | - | - | - |
|
S80623-10mg促销 |
99.70% | ￥180.00 ￥144.00 |
6 | - | - | - | - |
|
S80623-25mg促销 |
99.70% | ￥350.00 ￥280.00 |
6 | - | - | - | - |
|
S80623-50mg促销 |
99.70% | ￥610.00 ￥488.00 |
5 | - | - | - | - |
|
S80623-100mg促销 |
99.70% | ￥1100.00 ￥880.00 |
4 | - | - | - | - |
|
S80623-200mg促销 |
≥99% | ￥2100.00 ￥1680.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | INH1 specifically disrupts the Hec1/Nek2 interaction via direct Hec1 binding. INH1 shows promising cancer inhibition activity both in vitro and in vivo | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Apoptosis;Apoptosis;MicrotubuleAssociated | ||||||||||||||||||||
| 体内研究： | INH1 (50 or 100 mg/kg, i.p., every other day/25 cycles) inhibits tumor outgrowth in a xenografted breast cancer model in nude mice | ||||||||||||||||||||
| 参考文献： | 1. Wu G, et al. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res. 2008 Oct 15;68(20):8393-9. 2. Shilong Zheng, et al. Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion. ACS Med Chem Lett. 2013 Feb 14; 4(2): 191–196. 3. Yongxia Zhu, et al. Small Molecule TH-39 Potentially Targets Hec1/Nek2 Interaction and Exhibits Antitumor Efficacy in K562 Cells via G0/G1 Cell Cycle Arrest and Apoptosis Induction. Cell Physiol Biochem. 2016;40(1-2):297-308. | ||||||||||||||||||||
| 溶解性： | DMSO : 100 mg/mL (324.25 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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