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ZM 447439

    
≥98%

ZM 447439

源叶(MedMol)
S80647 一键复制产品信息
331771-20-1
C29H31N5O4
513.59
N-(4-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)phenyl)benzamide
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S80647-5mg买3赠1
≥98%

¥300.00

>10 - - - -
S80647-10mg买3赠1
≥98%

¥520.00

>10 - - - -
S80647-25mg买3赠1
≥98%

¥1150.00

>10 - - - -
S80647-50mg买3赠1
≥98%

¥1950.00

10 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
靶点: Apoptosis;Aurora Kinase;MEK;Src;Apoptosis;MEK;Src;AuroraKinase
细胞实验: Cell number is evaluated by crystal violet staining. In brief, cells in 96-well plates are fixed with 1% glutaraldehyde. Then cells are stained with 0.1% crystal violet. The unbound dye is removed by washing with water. Bound crystal violet is solubilized with 0.2% Triton X-100. Light extinction which increases linearly with the cell number is analyzed at 570 nm using an ELISA reader.(Only for Reference)
参考文献: 1. Ditchfield C, et al. J Cell Biol. 2003, 161(2), 267-280. 2. Zhang L, et al. J Obstet Gynaecol Res. 2011, 37(6), 591-600. 3. Teperek-Tkacz M, et al. Cell Cycle. 2010, 9(23), 4674-4687. 4. Georgieva I, et al. Neuroendocrinology. 2010, 91(2), 121-130.
溶解性: Soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.947 ml 9.735 ml 19.471 ml
5 mM 0.389 ml 1.947 ml 3.894 ml
10 mM 0.195 ml 0.974 ml 1.947 ml
50 mM 0.039 ml 0.195 ml 0.389 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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