| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S80770-1mg |
98.5% | ￥42.00 | 2 | - | - | - |
|
S80770-5mg |
98.5% | ￥135.00 | 2 | - | - | - |
|
S80770-10mg |
98.5% | ￥225.00 | 5 | - | - | - |
|
S80770-25mg |
98.5% | ￥460.00 | 7 | - | - | - |
|
S80770-50mg |
98.5% | ￥800.00 | 3 | - | - | - |
|
S80770-100mg |
≥98% | ￥1130.00 | 货期：2-3天 | - | - | - |
|
STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
| 产品描述： | STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml. | ||||||||||||||||||||
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| 靶点： | Ki: 80 ng/mL (CaM-KKα), 15 ng/mL (CaM-KKβ);CaMK;AMPK;Autophagy | ||||||||||||||||||||
| 参考文献： | 1. Tokumitsu H, et al. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8. 2. Kukimoto-Niino M, et al. Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609. J Biol Chem. 2011 Jun 24;286(25):22570-9. | ||||||||||||||||||||
| 溶解性： | DMSO : 6.25 mg/mL (19.89 mM; ultrasonic and warming and heat to 80°C) DMF : 5.56 mg/mL (17.69 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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