| 产品描述： | Sulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Acts as an antibacterial and antimicrobial. |
| 靶点： |
Bacterial;P450;Antibacterial |
| 参考文献： |
1. Chimalakonda KC, et al. Sulfaphenazole and α-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. Drug Metab Lett. 2013 Mar;7(1):34-8. 2. Hama S, et al. Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats. Biol Pharm Bull. 2012;35(10):1849-53. 3. BROWNE SG.Trial of a long-acting sulfonamide sulfaphenazole (Orisul, Ciba), in the treatment of leprosy. Int J Lepr. 1961 Oct-Dec;29:502-5. |
| 溶解性： |
DMSO : ≥ 100 mg/mL (318.11 mM) |
| 保存条件： |
2-8℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.181 ml |
15.905 ml |
31.811 ml |
| 5 mM |
0.636 ml |
3.181 ml |
6.362 ml |
| 10 mM |
0.318 ml |
1.591 ml |
3.181 ml |
| 50 mM |
0.064 ml |
0.318 ml |
0.636 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京