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• 产品描述： Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.

• 靶点： α2-adrenergic Receptor;AdrenergicReceptor

• 参考文献：
  1. Andorn, A.C., M.A. Carlson, and R.C. Gilkeson, Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity states with alpha 2-adrenergic selectivity and differing affinities for GTP. Life Sci, 1988. 43(22): p. 1805-12. 2. Cambridge, D., UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes. Eur J Pharmacol, 1981. 72(4): p. 413-5. 3. Chopin, P., F.C. Colpaert, and M. Marien, Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther, 1999. 288(2): p. 798-804.

• 溶解性： DMSO  :  50  mg/mL  (171.16  mM;  Need  ultrasonic)

• 保存条件： 2-8℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.423 ml	17.116 ml	34.231 ml
  5 mM	0.685 ml	3.423 ml	6.846 ml
  10 mM	0.342 ml	1.712 ml	3.423 ml
  50 mM	0.068 ml	0.342 ml	0.685 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 2. [IF=5.7] Xu Guiju et al."Hydroxylated hierarchical flower-like COF for solid-phase extraction of adrenergic receptor agonists in milk."MICROCHIMICA ACTA".2024 Jun;191(6):1-9

• 1. [IF=2.3] Aiqun Xiang et al."Ocular Posterior Segment Distribution and Pharmacokinetics of Brimonidine After Intravitreal Administration in Guinea Pigs."JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *