Dienogest 99.80%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80872-5mg促销 |
99.80% | ￥40.00 ￥30.00 |
8 | - | - | - | - |
|
S80872-10mg促销 |
99.80% | ￥50.00 ￥35.00 |
9 | - | - | - | - |
|
S80872-100mg促销 |
99.80% | ￥240.00 ￥110.00 |
2 | - | - | - | - |
|
S80872-250mg促销 |
99.80% | ￥490.00 ￥165.00 |
4 | - | - | - | - |
|
S80872-1g促销 |
99.80% | ￥1200.00 ￥355.00 |
2 | - | - | - | - |
|
| 产品描述： | Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia | ||||||||||||||||||||
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| 靶点： | Progesterone Receptor;Apoptosis;Estrogen/progestogenReceptor;ProgesteroneReceptor;Autophagy | ||||||||||||||||||||
| 体内研究： | Dienogest (1 mg/kg; p.o.; once daily for 14 days) regulates angiogenesis in ectopic endometrial lesions in rat endometrial autograft model | ||||||||||||||||||||
| 参考文献： | 1. Shimizu Y, et al. Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system. Steroids. 2011 Jan;76(1-2):60-7. 2. Katayama H, et al. Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model. Hum Reprod. 2010 Nov;25(11):2851-8. | ||||||||||||||||||||
| 溶解性： | DMSO : 25 mg/mL (80.28 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(2篇)
2. [IF=8.3] Yun-Yuan Tian et al."Paeonia × suffruticosa Andrews leaves improve endometriosis with anxiety/depression by regulating microglial polarization via JAK2/STAT3 pathway."PHYTOMEDICINE.2026 Jan;:157778
1. [IF=7.514] Suo Decheng et al."Trace analysis of progesterone and 21 progestins in milk by ultra-performance liquid chromatography coupled with high-field quadrupole-orbitrap high-resolution mass spectrometry."Food Chem. 2021 Nov;361:130115
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