| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S81049-5mg买3赠1 |
99.70% | ￥76.00 |
1 | - | - | - | - |
|
S81049-10mg买3赠1 |
99.70% | ￥126.00 |
1 | - | - | - | - |
|
S81049-50mg买3赠1 |
99.70% | ￥340.00 |
6 | - | - | - | - |
|
S81049-100mg买3赠1 |
99.70% | ￥492.00 |
7 | - | - | - | - |
|
S81049-200mg买3赠1 |
99.70% | ￥765.00 |
3 | - | - | - | - |
|
S81049-1g |
≥99% | ￥2000.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | Fidaxomicin (OPT-80), a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | DNA/RNA Synthesis;Bacterial;Apoptosis;Antibiotic;Apoptosis; DNA/RNASynthesis; Antibacterial; Antibiotic | ||||||||||||||||||||
| 体内研究： | Fidaxomicin (0-5 mg/kg, Orally, once a day for 5 days) completely prevents the lethality of the animals and prevents the occurrence of relapses in a hamster model for pseudomembranous colitis | ||||||||||||||||||||
| 参考文献： | 1. Poxton IR, et al. Fidaxomicin: a new macrocyclic, RNA polymerase-inhibiting antibiotic for the treatment of Clostridium difficile infections. Future Microbiol. 2010 Apr;5(4):539-48. 2. Tannock GW, et al. A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin. Microbiology (Reading). 2010 Nov;156(Pt 11):3354-3359. 3. Ackermann G, Löffler B, Adler D, Rodloff AC. In vitro activity of OPT-80 against Clostridium difficile. Antimicrob Agents Chemother. 2004 Jun;48(6):2280-2. 4. Ackermann G, et al. In vitro activity of OPT-80 against Clostridium difficile. Antimicrob Agents Chemother. 2004 Jun;48(6):2280-2. | ||||||||||||||||||||
| 溶解性： | DMSO : ≥ 33 mg/mL (31.19 mM) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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