| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S81168-2mg买3赠1 |
99.00% | ￥160.00 |
9 | - | - | - | - |
|
S81168-5mg买3赠1 |
99.00% | ￥224.00 |
9 | - | - | - | - |
|
S81168-10mg买3赠1 |
99.00% | ￥320.00 |
6 | - | - | - | - |
|
S81168-25mg买3赠1 |
99.00% | ￥620.00 |
10 | - | - | - | - |
|
S81168-50mg买3赠1 |
99.00% | ￥1200.00 |
4 | - | - | - | - |
|
S81168-100mg买3赠1 |
≥99% | ￥2240.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | CPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potential chemopreventive and antineoplastic activities, and has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. | ||||||||||||||||||||
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| 靶点： | Apoptosis;Dehydrogenase;Mitochondrial Metabolism;Apoptosis; Dehydrogenase; MitochondrialMetabolism | ||||||||||||||||||||
| 体内研究： | CPI-613 (25 mg/kg) has potent anticancer activity in a human tumor xenograft model of of a pancreatic tumor cell (BxPC-3). Similarly, CPI-613 (10 mg/kg) also produces significant tumor growth inhibition of H460 human non-small cell lung carcinoma in mouse model. Besides, CPI-613 produces little or no side-effect toxicity in expected therapeutic dose ranges in large animal models and has the maximum tolerated dose of 100 mg/kg in mice. | ||||||||||||||||||||
| 参考文献： | 1.Zachar Z, et al. J Mol Med (Berl). 2011, 89(11), 1137-1148. | ||||||||||||||||||||
| 溶解性： | DMSO:78 mg/mL (200.72 mM) H2O:<1 mg/mL Ethanol:78 mg/mL (200.72 mM) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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