| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S81183-10mg买3赠1 |
99.80% | ￥170.00 |
>10 | - | - | - | - |
|
S81183-50mg买3赠1 |
99.80% | ￥560.00 |
>10 | - | - | - | - |
|
S81183-250mg买3赠1 |
99.80% | ￥2010.00 |
>10 | - | - | - | - |
|
S81183-500mg买3赠1 |
99.80% | ￥3500.00 |
>10 | - | - | - | - |
|
S81183-1g |
99.80% | ￥5940.00 |
>10 | - | - | - | - |
|
| 产品描述： | Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells | ||||||||||||||||||||
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| 靶点： | Fungal;Autophagy;Apoptosis;p38 MAPK;Microtubule/Tubulin;Antibiotic; Antifungal | ||||||||||||||||||||
| 体内研究： | Sertaconazole nitrate (1% (w/v); apply to the left ear, once) suppresses of TPA-induced ear edema CD-1 mice | ||||||||||||||||||||
| 参考文献： | 1. Carrillo-Muñoz AJ, et al. In-vitro antifungal activity of sertaconazole, econazole, and bifonazole against Candida spp. J Antimicrob Chemother. 1995 Oct;36(4):713-6. 2. Sur R, et al. Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway. J Invest Dermatol. 2008 Feb;128(2):336-44. 3. Sebastian J, et al. Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly. Naunyn Schmiedebergs Arch Pharmacol. 2021 Jun;394(6):1231-1249. 4. Zhang W, et al. Sertaconazole provokes proapoptotic autophagy via stabilizing TRADD in nonsmall cell lung cancer cells. MedComm (2020). 2021 Dec 16;2(4):821-837. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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