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Tolimidone

    
≥98%(HPLC)

Tolimidone

源叶(MedMol)
S81472 一键复制产品信息
41964-07-2
C11H10N2O2
202.21
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
S81472-10mg促销
≥98%(HPLC)

¥462.00 ¥416.00

1 - - 3 -
S81472-50mg促销
≥98%(HPLC)

¥1570.00 ¥1410.00

4 - - - -
S81472-100mg促销
≥98%(HPLC)

¥2500.00 ¥2250.00

4 - - - -
S81472-250mg促销
≥98%(HPLC)

¥5000.00 ¥4500.00

2 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM.
靶点: EC50: 63 nM (Lyn kinase);Src
体内研究: Administration of Tolimidone (MLR-1023) (30 mg/kg i.p.) significantly (p<0.05) lowers blood glucose levels to 148 and 158 mg/dL, 30 and 90 min after administration, respectively. Tolimidone significantly increases adipocyte differentiation and adiponectin production by 3.7- and 19-fold, respectively. Tolimidone elicits a dose-dependent potentiation of the insulin response, with a maximal effect observed with a dose level of 30 mg/kg
参考文献: 1. Saporito MS, et al. MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro that improves glucose tolerance in vivo. J Pharmacol Exp Ther. 2012 Jul;342(1):15-22. 2. Ochman AR, et al. The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes. J Pharmacol Exp Ther. 2012 Jul;342(1):23-32.
溶解性: Soluble  in  DMSO
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 4.945 ml 24.727 ml 49.454 ml
5 mM 0.989 ml 4.945 ml 9.891 ml
10 mM 0.495 ml 2.473 ml 4.945 ml
50 mM 0.099 ml 0.495 ml 0.989 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

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