货号	规格	价格	上海	北京	珠海	重庆	武汉
S81499-10mg促销	99.50%	￥150.00 ￥120.00 S81499-10mg ￥120.00 现货	3002 >10	-	-	-	-
S81499-50mg促销	99.50%	￥500.00 ￥400.00 S81499-50mg ￥400.00 现货	602 >10	-	-	-	-
S81499-250mg促销	99.50%	￥1400.00 ￥1120.00 S81499-250mg ￥1120.00 现货	127 >10	-	-	-	-
S81499-1g促销	99.50%	￥3800.00 ￥3040.00 S81499-1g ￥3040.00 现货	36 >10	-	-	-	-

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产品描述：

Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase

靶点：

Ser/Thr Protease;SARS-CoV;Serine/threoninkinase; SARS-CoV; SodiumChannel

体内研究：

Camostat mesilate (30 mg/kg; p.o.; twice a day for 9 days) blocks the spread and pathogenesis of SARS-CoV in a pathogenic mouse model

参考文献：

1. Gibo J, et al. Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. Lab Invest. 2005;85(1):75‐89. 2. Uno Y. Camostat mesilate therapy for COVID-19 [published online ahead of print, 2020 Apr 29]. Intern Emerg Med. 2020;1‐2. 3. Coote K, et al. Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. J Pharmacol Exp Ther. 2009;329(2):764‐774. 4. Zhou Y, Vedantham P, Lu K, et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015;116:76‐84.

溶解性：

DMSO : 125 mg/mL (252.77 mM; Need ultrasonic) H2O : ≥ 50 mg/mL (101.11 mM)

保存条件：

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.022 ml	10.111 ml	20.222 ml
5 mM	0.404 ml	2.022 ml	4.044 ml
10 mM	0.202 ml	1.011 ml	2.022 ml
50 mM	0.04 ml	0.202 ml	0.404 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(1篇)

1. [IF=4.132] Shuang Liu et al."Comparison of Physicochemical and Bioactive Properties of Polysaccharides from Massa Medicata Fermentata and Its Processed Products."ACS Omega.2022;XXXX(XXX):XXX-XXX

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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分子摩尔量

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Camostat Mesilate