| 产品描述： | D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. |
| 靶点： |
TRP Channel;TRP/TRPVChannel |
| 体外研究： |
D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH |
| 参考文献： |
1. enteric-coated TRPM8 agonist D-3263 hydrochloride |
| 溶解性： |
soluble in DMSO |
| 保存条件： |
-20℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.439 ml |
12.197 ml |
24.393 ml |
| 5 mM |
0.488 ml |
2.439 ml |
4.879 ml |
| 10 mM |
0.244 ml |
1.22 ml |
2.439 ml |
| 50 mM |
0.049 ml |
0.244 ml |
0.488 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京