| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S81731-1mg买3赠1 |
99.30% | ￥100.00 |
6 | - | - | - | - |
|
S81731-2mg买3赠1 |
99.30% | ￥180.00 |
7 | - | - | - | - |
|
S81731-5mg买3赠1 |
99.30% | ￥320.00 |
7 | - | - | - | - |
|
S81731-10mg买3赠1 |
99.30% | ￥580.00 |
1 | - | - | - | - |
|
S81731-25mg买3赠1 |
≥98% | ￥1000.00 |
货期：2-3天 | - | - | - | - |
|
S81731-50mg买3赠1 |
≥98% | ￥1640.00 |
货期：2-3天 | - | - | - | - |
|
S81731-100mg |
≥98% | ￥2390.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | VUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pKi of 7.46. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | pKi: 7.46 (H4);HistamineReceptor | ||||||||||||||||||||
| 体外研究： | UF10460 binds to rat H3 and H4 receptor with pKi values of 5.75, and 7.46, respectively. VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor | ||||||||||||||||||||
| 体内研究： | HCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120 | ||||||||||||||||||||
| 参考文献： | 1. Coruzzi G, et al. Selective histamine H3 and H4 receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach. Eur J Pharmacol. 2011 Nov 1;669(1-3):121-7. | ||||||||||||||||||||
| 溶解性： | soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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