货号	规格	价格	上海	北京	珠海	重庆	武汉
S82090-5mg买3赠1	99.90%	￥480.00 S82090-5mg ￥480.00 现货（买3赠1）	382 >10	-	-	-	-
S82090-10mg买3赠1	99.90%	￥640.00 S82090-10mg ￥640.00 现货（买3赠1）	190 >10	-	-	-	-
S82090-25mg买3赠1	99.90%	￥1120.00 S82090-25mg ￥1120.00 现货（买3赠1）	79 >10	-	-	-	-
S82090-50mg买3赠1	99.90%	￥1760.00 S82090-50mg ￥1760.00 现货（买3赠1）	42 >10	-	-	-	-

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产品描述：

Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis, suppresses cell cycle progression, and inhibits DNA synthesis

靶点：

Human Endogenous Metabolite;Apoptosis; ReactiveOxygenSpecies; DNA/RNASynthesis; EndogenousMetabolite; Autophagy; DrugMetabolite

体内研究：

The volume of paw edema is reduced at 1 h after oral administration of urolithin A. In addition, plasma in treated mice exhibited significant oxygen radical antioxidant capacity (ORAC) scores with high plasma levels of the unconjugated form at 1 h after oral administration of urolithin A

参考文献：

1. Gong Z, et al. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice. 2. Wang Y, et al. In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells. Toxicol In Vitro. 2015 Aug;29(5):1107-15. 3. Zhao W, et al. Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620colorectal cancer cells. Mol Carcinog. 2018 Feb;57(2):193-200. 4. Ishimoto H, et al. In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5901-4. 5. Qiu Z, et al. In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells. Food Chem Toxicol. 2013 Sep;59:428-37. 6. González-Sarrías A, et al. Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism.Eur J Nutr. 2017 Mar;56(2):831-841.

溶解性：

DMSO : 30 mg/mL (131.46 mM; Need ultrasonic)

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.382 ml	21.911 ml	43.821 ml
5 mM	0.876 ml	4.382 ml	8.764 ml
10 mM	0.438 ml	2.191 ml	4.382 ml
50 mM	0.088 ml	0.438 ml	0.876 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(1篇)

1. Li, P, Du, R, Chen, Z, et al. Punicalagin is a neuraminidase inhibitor of influenza viruses. J Med Virol. 2021; 93: 3465– 3472. https://doi.org/10.1002/jmv.26449

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

Urolithin A

3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one

参考文献(1篇)

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)